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6β-Oxymorphol (CRM), also known as 6β-hydroxymethylmorphinan, is a certified reference material classified as an opioid. It is a metabolite of oxymorphone, which is an opioid analgesic used for the treatment of moderate to severe pain. 6β-Oxymorphol is primarily used in research and forensic applications due to its association with opioid substances.

54934-75-7

54934-75-7 Suppliers

This product is a nationally controlled contraband or patented product, and the Lookchem platform doesn't provide relevant sales information.

54934-75-7 Usage

Uses

Used in Research Applications:
6β-Oxymorphol is used as a research compound for studying the metabolism, pharmacokinetics, and pharmacodynamics of opioids, particularly oxymorphone. It helps researchers understand the metabolic pathways and the effects of opioids on the human body.
Used in Forensic Applications:
6β-Oxymorphol is used as a forensic tool in the detection and identification of opioid use, abuse, or overdose cases. It serves as a biomarker for the presence of oxymorphone in biological samples, such as blood, urine, or hair, aiding in the investigation of drug-related crimes and fatalities.
Used in Drug Testing and Analysis:
6β-Oxymorphol is used as a reference material in the development and validation of drug testing methods and analytical techniques. It helps ensure the accuracy and reliability of drug tests by providing a known standard for comparison and calibration of testing equipment.
Used in Pharmaceutical Development:
6β-Oxymorphol is used as a starting material or intermediate in the synthesis of new opioid medications. Researchers can use 6b-Oxymorphol to develop novel drugs with improved efficacy, safety, and reduced potential for abuse.
Used in Quality Control and Standardization:
6β-Oxymorphol is used as a certified reference material for quality control and standardization of opioid-related products and testing methods. It ensures that the products and methods meet the required standards and are consistent across different laboratories and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 54934-75-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,9,3 and 4 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 54934-75:
(7*5)+(6*4)+(5*9)+(4*3)+(3*4)+(2*7)+(1*5)=147
147 % 10 = 7
So 54934-75-7 is a valid CAS Registry Number.

54934-75-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 6β-Oxymorphol

1.2 Other means of identification

Product number -
Other names 6alpha-Hydroxytestosterone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:54934-75-7 SDS

54934-75-7Relevant academic research and scientific papers

Stereo-selective synthesis method for 6beta-hydroxyl-7,8-dihydro-morphine derivatives

-

, (2019/10/23)

The invention discloses a stereo-selective synthesis method for 6beta-hydroxyl-7,8-dihydro-morphine derivatives. The synthesis method comprises the following steps: (i) reducing a compound of a formula VI into a compound of a formula VII by sodium borohydride in a hydrophilic organic solvent in the presence of catalytic C1-C4 alkanoic acid; (ii) separating the compound of the formula VII obtainedin the step (i), thereby obtaining the compound of a formula VIII. Definitions of substituent groups in the formulas VI, VII and VIII are as shown in the description in detail.

Process for the Preparation of 6-Beta Hydroxy Morphinan Compounds

-

Page/Page column 7-8, (2009/12/27)

The invention provides processes for the conversion of a 6-keto morphinan to a 6-hydroxy morphinan. In particular, the invention provides a stereoselective process for the conversion of a 6-keto morphinan to a 6-beta-hydroxy morphinan.

Probes for narcotic receptor mediated phenomena. 24. synthesis, single crystal X-ray analyses, in vitro and in vivo properties of 6α-and 6β-IODO-3,14-dihydroxy-17-methyl-4,5α-epoxymorphinans

Kayakiri, Hiroshi,Jacobson, Arthur E.,Rice, Kenner C.,Rothman, Richard B.,Xu, Heng,Flippen-Anderson, Judith L.,George, Clifford,Aceto, Mario D.,Bowman, Edward R.,Harris, Louis S.,May, Everette L.,Partilla, John S.,Becketts, Karen

, p. 427 - 438 (2007/10/03)

The 6α- and 6β-iodo-3,14-dihydroxy-17-methyl-4,5α-epoxymorphinans, potential SPECT ligands, were synthesized and found to be μ-selective opioids, more potent in vitro and in vivo than their 6-hydroxy relatives. Single-crystal analysis showed that the 6α- and 6β-iodine atoms are spatially closely located although the C-ring conformations of these compounds are quite different (twist-boat form vs. chair). These epimeric conformational differences were not reflected in their binding affinities.

Stereoselective synthesis of β-naltrexol, β-nalaxol, β-naloxamine, β-naltrexamine and related compounds by the application of the Mitsunobu reaction

Simon,Hostzafi,Makleit

, p. 9757 - 9768 (2007/10/02)

As a continuation of our work, aimed at adopting the Mitsonobu reaction in the morphine series, a few representatives of dihydroisocodeines and dihydroisomorphines and their 14β-hydroxy analogues were prepared. p-Nitrobenzoic acid was used as carboxylic acid and the prepared esters were cleaved to obtain the title compounds. Using phthalimide as acidic component several new 6β-phthalimidodihydromorphine and dihydrocodeine derivatives and their 14β-hydroxy analogues have been synthesized. Cleavage of the phthalimido derivatives with hydrazine hydrate afforded the corresponding 6β-amino derivatives.

SYNTHESIS OF N-DEMETHYL-N-SUBSTITUTED 14-β-HYDROXY-ISOMORPHINE AND DIHYDROISOMORPHINE DERIVATIVES

Hosztafi, Sandor,Simon, Csaba,Makleit, Sandor

, p. 1509 - 1520 (2007/10/02)

Some new representatives (3e-3h,5g) of a new group of structurally related morphine-agonist and antagonist compounds have been prepared in stereochemically homogeneous forms.Application of the Mitsunobu-reaction for suitable codeine derivatives (1a-1d) ga