54951-59-6Relevant academic research and scientific papers
Nucleophilic Organic Base DABCO-Mediated Chemospecific Meinwald Rearrangement of Terminal Epoxides into Methyl Ketones
Li, Siqi,Shi, Yi,Li, Pingfan,Xu, Jiaxi
, p. 4443 - 4450 (2019/04/30)
Nucleophilic organic base DABCO (1,4-diazabicyclo[2.2.2]octane)-mediated Meinwald rearrangement of various epoxides was investigated. 2-Aryl-, alkenyl-, and alkynylepoxides generate the corresponding methyl ketones chemospecifically in good to excellent yields. The current DABCO-mediated Meinwald rearrangement of epoxides features readily accessible starting materials, a wide substrate scope, a transition-metal- and acid-free environment, and chemospecificity in the isomerization of epoxides.
Organic Compounds
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Page/Page column 8-9, (2010/05/13)
Disclosed are compounds having the ability to inhibit cytochrome P450 2A6, 2A13, and/or 2B6 and tobacco products comprising them. Also disclosed are pharmaceutical compositions comprising them.
CuH-catalyzed enantioselective 1,2-reductions of α,β-unsaturated ketones
Moser, Ralph,Boskovia, Zarko V.,Crowe, Christopher S.,Lipshutz, Bruce H.
supporting information; experimental part, p. 7852 - 7853 (2010/08/04)
The first study on a general technology for arriving at valued nonracemic allylic alcohols using asymmetric ligand-accelerated catalysis by copper hydride is described.
ORGANIC COMPOUNDS
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Page/Page column 28-29, (2008/12/04)
Disclosed are compounds having the ability to modulate, namely to improve, enhance and or modify fragrance compositions due to their ability to inhibit cytochrome P450 enzymes, e.g. CYP2A13 and CYP2B6.
Stereospecific synthesis of methyl vinyl ketones
Chamakh,M'hirsi,Amri
, p. 1157 - 1163 (2007/10/03)
A stereospecific synthesis of enones 3 by coupling reaction of α-acetoxy alkyl methyl vinyl ketones 2 and Gilman or Grignard reagents in the presence of a catalytic amount of copper(I) salt at low temperature, is described.
