54953-13-8

Upstream product

• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 67-66-3 chloroform 
• 7789-60-8 phosphorus tribromide 
• 503-17-3 dimethylacetylene 
• 13139-86-1 4-methoxyphenyl magnesium bromide 

Downstream Products

• 65026-51-9 meso-2,3-bis(4-methoxyphenyl)butane 
• 2962-14-3 meso-Butestrol 
• 15624-00-7 (+/-)-erythro-2-<4-(2-Diethylamino-ethoxy)-phenyl>-3-(4-hydroxy-phenyl)-butan 
• 15515-41-0 meso-2,3-Bis-<4-(2-dimethylamino-ethoxy)-phenyl>-butan 
• 15515-42-1 (+/-)-erythro-2-<4-(2-Dimethylamino-ethoxy)-phenyl>-3-(4-hydroxy-phenyl)-butan 
• 99553-77-2 (3S,5S)-3,5-Bis-(4-methoxy-phenyl)-3,5-dimethyl-[1,2,4]trioxolane 
• 99553-77-2 (3R,5S)-3,5-Bis-(4-methoxy-phenyl)-3,5-dimethyl-[1,2,4]trioxolane 
• 99553-75-0 cis-2,3-bis(4'-methoxyphenyl)-2,3-dimethyloxirane 

Relevant academic research and scientific papers

A heterobimetallic complex featuring a Ti-Co multiple bond and its application to the reductive coupling of ketones to alkenes

To explore metal-metal multiple bonds between first row transition metals, Ti/Co complexes supported by two phosphinoamide ligands have been synthesized and characterized. The Ti metalloligand Cl2Ti(XylNPiPr2)2 (1) was treated with CoI2 under reducing conditions, permitting isolation of the Ti/Co complex [(μ-Cl)Ti(XylNPiPr2)2CoI]2 (2). One electron reduction of complex 2 affords ClTi(XylNPiPr2)2CoPMe3 (3), which features a metal-metal triple bond and an unprecedentedly short Ti-Co distance of 2.0236(9) ?. This complex is shown to promote the McMurry coupling reaction of aryl ketones into alkenes, with concomitant formation of the tetranuclear complex [Ti(μ3-O)(NXylPiPr2)2CoI]2 (4). A cooperative mechanism involving bimetallic C=O bond activation and a cobalt carbene intermediate is proposed.

Ionic-liquid-influenced expeditious and stereoselective synthesis of olefins

1-Butyl-3-methylimidazolium chloroaluminate, [bmim]Cl·.AlCl3 (molar fraction, N=0.67), ionic liquid has been used in combination with metallic Zn for the reductive coupling of carbonyl compounds to synthesize symmetrical olefins, with the Z-isomer formed predominantly. The ionic liquid played a dual role of Lewis acid catalyst and solvent. Copyright Taylor & Francis Group, LLC.

Stereochemistry and Side Products in Reductive Coupling of Alkyl Aryl Ketones to 1,2-Dialkyl-1,2-diarylethylenes

The reductive coupling of alkyl aryl ketones 1 - 3 and 7 - 9 by low valent titanium salts yields predominantly the (Z)-isomers of 11 - 13 and 17 - 19.Evidence is given by 1H NMR spectroscopy.This behavior can be explained by ?-complex formation of phenyl rings with Ti0.Severe steric hindrance, however, favors the (E)-isomers ( -> 14 and 15).Donor groups in p-position, particularly, give increasing amounts of pinacols, 23 - 27, which undergo rearrangement to the ketones 28 and 29.