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(R)-3-Methoxy-pyrrolidine-1-carboxylic acid tert-butyl ester is a chiral ester derivative with the molecular formula C10H19NO3, serving as a crucial building block in organic synthesis and pharmaceutical research.
Used in Pharmaceutical Industry:
(R)-3-Methoxy-pyrrolidine-1-carboxylic acid tert-butyl ester is used as a chiral building block for the synthesis of biologically active molecules and pharmaceutical intermediates, contributing to the development of various drugs.
Used in Drug Preparation:
(R)-3-Methoxy-pyrrolidine-1-carboxylic acid tert-butyl ester is used as a precursor in the preparation of antihypertensive agents and other therapeutic agents, playing a significant role in the advancement of medicinal chemistry.
Used in Agrochemical Industry:
(R)-3-Methoxy-pyrrolidine-1-carboxylic acid tert-butyl ester has potential applications in the field of agrochemicals, where it can be utilized for the synthesis of active ingredients in pesticides and other agricultural products.
Used as a Chiral Reagent:
(R)-3-Methoxy-pyrrolidine-1-carboxylic acid tert-butyl ester is used as a chiral reagent in chemical reactions, facilitating the synthesis of enantiomerically pure compounds for various applications.

549532-08-3

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549532-08-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 549532-08-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,4,9,5,3 and 2 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 549532-08:
(8*5)+(7*4)+(6*9)+(5*5)+(4*3)+(3*2)+(2*0)+(1*8)=173
173 % 10 = 3
So 549532-08-3 is a valid CAS Registry Number.

549532-08-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 3R-methoxypyrrolidine-1-carboxylic acid tert-butyl ester

1.2 Other means of identification

Product number -
Other names (3R)-3-methoxy-pyrrolidine-1-carboxylic acid tert-butyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:549532-08-3 SDS

549532-08-3Relevant articles and documents

4-PYRIDONE COMPOUND OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION AND FORMULATION INCLUDING SAME

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Paragraph 0494; 0499-0502; 0540-0543, (2020/02/08)

An object of the present invention is to provide a compound or a salt thereof having anti-HBV activity, a pharmaceutical composition, an anti-hepatitis B virus agent, a production inhibitor of DNA of a hepatitis B virus, and a production or secretion inhibitor of a hepatitis B surface antigen. According to the present invention, provided are a compound represented by General Formula [1] or a salt thereof: (in the formula, R1 represents a benzothiazolyl group which may be substituted (in which a carbon atom constituting the 6-membered ring of the benzothiazolyl group of R1 is bonded to the nitrogen atom of the pyridone ring); R2 represents a C2-6 alkenyl group which may be substituted, or the like; and R3 represents a hydrogen atom or the like).

COMPOUNDS AND THEIR METHODS OF USE

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Page/Page column 167, (2018/09/08)

The present invention is directed to, in part, fused heteroaryl compounds and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including Dravet syndrome or epilepsy are also provided herein.

AMINOPYRIMIDINE HETEROCYCLIC COMPOUND WITH ADENOSINE RECEPTOR ANTAGONISTIC ACTIVITY

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, (2017/06/23)

Disclosed hereinis an aminopyrimidine heterocyclic compound with adenosine receptor antagonistic activity, comprising a compound of the general formula (I), or a pharmaceutically acceptable salt thereof. The aminopyrimidine heterocyclic compound with adenosine receptor antagonistic activitydisclosed herein can be used as an effective adenosine receptor antagonist, and can be used for the treatment or prevention of disorders caused by abnormal level of adenosine.

Protecting-group-free catalytic asymmetric total synthesis of (-)-rosmarinecine

Nemoto, Hiroyuki,Tanimoto, Kouichi,Kanao, Yukiko,Omura, Sohei,Kita, Yasuyuki,Akai, Shuji

experimental part, p. 7295 - 7301 (2012/09/21)

The protecting-group-free asymmetric total synthesis of (-)-rosmarinecine was achieved in only four steps from the commercially available (±)-3-hydroxypyrrolidine hydrochloride (2a). The key steps include the direct oxidation of (±)-2a to (±)-3-hydroxy-1-pyrroline N-oxide (1a) using the Davis reagent and the domino reaction; viz., the lipase-catalyzed dynamic kinetic resolution of (±)-1a with 1-ethoxyvinyl ethyl maleate followed by the intramolecular [3+2] dipolar cycloaddition reaction of the generated optically active ester. Some insights into the mechanism of the racemization of the optically active 1a, observed during the enzymatic process, were also obtained.

OXAZOLE DERIVATIVES AS HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES

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Page/Page column 66, (2008/06/13)

The present invention discloses novel aryl oxazole compounds of Formula I (I), or pharmaceutically acceptable salts thereof, which have histamine-H3 receptor antagonist or inverse agonist activity, as well as methods for preparing and using such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I as well as methods of using these compositions to treat obesity, cognitive deficiencies, narcolepsy, and other histamine H3 receptor-related diseases. Formula I (I) or a pharmaceutically acceptable salt thereof, wherein: m is independenlly at each occurrence 1, 2, or 3, Z independently represents carbon (substituted with hydrogen or the optional substituents indicated herein) or nitrogen, provided that when Z is nitrogen then R6 is not attached to Z; R1 and R2 are independently -(C1-C7) alkyl(optionally substituted with one to three halogens), or R1 and R2 and the nitrogen to which they are attached form an azetidinyl ring, a pyrrolidinyl ring, or a piperidinyl ring, wherein further the azetidinyl, pyrrolidinyl, or piperidinyl ring so formed may be optionally substituted one to three times with R5; R6 is independently at each occurrence -H, -halogen, or -CH3.

5,7-DIAMINOPYRAZOLO [4,3-d] PYRIMIDINES WITH PDE-5 INHIBITING ACTIVITY

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Page/Page column 78, (2008/06/13)

This invention relates to compounds of formula (I).

PYRAZOLO`4,3-D! PYRIMIDINES

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Page/Page column 125, (2008/06/13)

This invention relates to compounds of formula (I).

PYRAZOLE DERIVATIVE

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Page/Page column 97, (2008/06/13)

Not available

5,7-DIAMINOPYRAZOLO`4,3-D!PYRIMIDINES USEFUL IN THE TREATMENT OF HYPERTENSION

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Page 172-173, (2008/06/13)

This invention relates to compounds of formula (I).

PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE

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Page 56, (2008/06/13)

Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are inhibitors of glycogen phosphorylase and are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, and as cardioprotectants.

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