54970-85-3

Basic information

• Product Name: 3-(2-methylphenyl)-1,2,3-benzotriazin-4(3H)-one
• CAS NO: 54970-85-3
• Molecular Formula: C₁₄H₁₁N₃O
• Molecular Weight: 237.2566
• Mol File: 54970-85-3.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 385.1°C at 760 mmHg
• Flash Point: 186.7°C
• Density: 1.25g/cm³
• Vapor Pressure: 3.9E-06mmHg at 25°C
• Refractive Index: 1.664
• CAS DataBase Reference: 3-(2-methylphenyl)-1,2,3-benzotriazin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-methylphenyl)-1,2,3-benzotriazin-4(3H)-one(54970-85-3)
• EPA Substance Registry System: 3-(2-methylphenyl)-1,2,3-benzotriazin-4(3H)-one(54970-85-3)

Safety Data

• Hazardous Substances Data: 54970-85-3(Hazardous Substances Data)

Upstream product

• 4943-85-5 2-amino-N-(2-methylphenyl)benzamide 
• 118-48-9 isatoic anhydride 
• 527-85-5 o-Methylbenzamid 
• 90-16-4 1,2,3-benzotriazin-4(3H)-one 
• 16419-60-6 2-Methylphenylboronic acid 
• 201230-82-2 carbon monoxide 
• 1242566-94-4 C₁₃H₁₂BrN₃ 
• 615-43-0 2-iodophenylamine 
• 95-53-4 o-toluidine 
• 615-36-1 2-bromoaniline 
• 134-20-3 2-carbomethoxyaniline 
• 111589-24-3 2-(3-o-tolyl-triazenyl)-benzoic acid methyl ester 

Downstream Products

• 42970-52-5 (+/-)-5-(2-o-tolyl)phenanthridin-6(5H)-one 

Relevant articles and documents

One-pot synthesis ofN-substituted benzannulated triazolesviastable arene diazonium salts

A mild and effective one-pot synthesis of 1,2,3-benzotriazin-4(3H)-ones and benzothiatriazine-1,1(2H)-dioxide analogues has been developed. The method involves the diazotisation and subsequent cyclisation of 2-aminobenzamides and 2-aminobenzenesulfonamidesviastable diazonium salts, prepared using a polymer-supported nitrite reagent andp-tosic acid. The transformation was compatible with a wide range of aryl functional groups and amide/sulfonamide-substituents and was used for the synthesis of pharmaceutically important targets. The synthetic utility of the one-pot diazotisaton-cyclisation process was further demonstrated with the preparation of an α-amino acid containing 1,2,3-benzotriazin-4(3H)-one.

Nickel-Catalyzed Denitrogenative Annulation of 1,2,3-Benzotriazin-4-(3H)-ones with Benzynes for Construction of Phenanthridinone Scaffolds

The synthesis of phenanthridinones via denitrogenative annulation of 1,2,3-benzotriazin-4-(3H)-ones with arynes catalysed by Ni(0)/dppm was successfully developed. A variety of phenanthridinones were prepared in good to excellent yields. Based on this method, nature product, N-methylcrinasidine, was synthesized. (Figure presented.).

Selective Synthesis of 3-Arylbenzo-1,2,3-triazin-4(3H)-ones and 1-Aryl-(1H)-benzo-1,2,3-triazoles from 1,3-Diaryltriazenes through Pd(0) Catalyzed Annulation Reactions

Pd(0) catalyzed carbonylative annulation reaction of 1-(2-iodophenyl)-3-aryltriaz-1-enes in the presence of DABCO and 1 atm of carbon monoxide in toluene at 80 °C gave the corresponding 3-arylbenzo-1,2,3-triazin-4(3H)-ones with high selectivity and in exc