Suxamethonium bromide, also known as succinylcholine, is a neuromuscular blocking agent characterized by its ability to induce transient muscle relaxation during general anesthesia or to facilitate endotracheal intubation. It functions by mimicking the action of acetylcholine at the neuromuscular junction, leading to a brief period of muscle paralysis. This property is crucial for medical procedures that require controlled muscle relaxation. Its rapid metabolism by plasma cholinesterases ensures a short duration of action, typically 5-10 minutes, making it a preferred choice in certain clinical scenarios.
55-94-7
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Basic information
- Product Name: suxamethonium bromide
- Synonyms: suxamethonium bromide;Brevidil M;Myorelaxin;Suxamethonium dibromide
- CAS NO:55-94-7
- Molecular Formula: 2Br*C14H30N2O4
- Molecular Weight: 450.207
- EINECS: 200-248-1
- Product Categories: N/A
- Mol File: 55-94-7.mol
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Chemical Properties
- Melting Point: 225°
- Boiling Point: °Cat760mmHg
- Flash Point: °C
- Appearance: /
- Density: g/cm3
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: suxamethonium bromide(CAS DataBase Reference)
- NIST Chemistry Reference: suxamethonium bromide(55-94-7)
- EPA Substance Registry System: suxamethonium bromide(55-94-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- RIDADR: 3249
- WGK Germany:
- RTECS:
- HazardClass: 6.1(b)
- PackingGroup: III
- Hazardous Substances Data: 55-94-7(Hazardous Substances Data)
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55-94-7 Usage
Uses
Used in Medical and Surgical Procedures:Suxamethonium bromide is used as a muscle relaxant for facilitating [intubation or surgery] because of its ability to cause transient depolarization and paralysis of the skeletal muscles. This allows for the safe and effective intubation of patients or the performance of surgical procedures that require controlled muscle relaxation.
Used in Anesthesia:
In the field of anesthesia, suxamethonium bromide is used as an adjunct to general anesthesia for [inducing muscle relaxation] during surgical procedures. Its rapid onset and short duration of action make it suitable for situations where brief paralysis is required.
Used in Emergency Medicine:
Suxamethonium bromide is also used in emergency medicine as a rapid-sequence intubation agent, facilitating the safe and swift intubation of patients in critical conditions, such as those experiencing respiratory distress or requiring immediate airway protection.
Caution:
While suxamethonium bromide is effective for its intended uses, it is associated with potential side effects such as muscle pain, hyperkalemia, and malignant hyperthermia. Therefore, it is crucial to exercise caution in patients with certain medical conditions, including burns, neuromuscular diseases, or electrolyte imbalances, to mitigate the risk of adverse reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 55-94-7 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 5 and 5 respectively; the second part has 2 digits, 9 and 4 respectively.Calculate Digit Verification of CAS Registry Number 55-94:
(4*5)+(3*5)+(2*9)+(1*4)=57
57 % 10 = 7
So 55-94-7 is a valid CAS Registry Number.
InChI:InChI=1/C14H30N2O4.2BrH/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2
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suxamethonium bromide
