5502-75-0

Basic information

• Product Name: 4-(1-Methylethyl)cyclohexanemethanol
• Synonyms: 4-(1-Methylethyl)cyclohexanemethanol;Hydroxymethyl isopropyl cyclohexane;4-Isopropylcyclohexylmethanol;(4-propan-2-ylcyclohexyl)methanol
• CAS NO: 5502-75-0
• Molecular Formula: C₁₀H₂₀O
• Molecular Weight: 156.2652
• Mol File: 5502-75-0.mol

Chemical Properties

• Boiling Point: 224 ºC
• Flash Point: 97 ºC
• Appearance: /
• Density: 0.882
• Vapor Pressure: 0.0192mmHg at 25°C
• Refractive Index: 1.4682
• PKA: 15.05±0.10(Predicted)
• CAS DataBase Reference: 4-(1-Methylethyl)cyclohexanemethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-Methylethyl)cyclohexanemethanol(5502-75-0)
• EPA Substance Registry System: 4-(1-Methylethyl)cyclohexanemethanol(5502-75-0)

Safety Data

• Hazardous Substances Data: 5502-75-0(Hazardous Substances Data)

Usage

Uses

Used in Insect Repellent Products:
4-(1-Methylethyl)cyclohexanemethanol is used as an insect repellent ingredient for its effective alternative to synthetic insect repellents. It is popular in many commercial insect repellent products due to its low toxicity and natural origin.
Used in Perfumes and Fragrances:
In the fragrance industry, 4-(1-Methylethyl)cyclohexanemethanol is used as a fragrance ingredient for its appealing minty scent. It adds a pleasant aroma to perfumes and other fragranced products, enhancing their overall scent profile.

InChI:InChI=1/C10H20O/c1-8(2)10-5-3-9(7-11)4-6-10/h8-11H,3-7H2,1-2H3

Upstream product

• 122-03-2 (4-isopropylbenzaldehyde) 
• 116473-59-7 4-(1-methoxy-1-methylethyl)-benzaldehyde dimethyl acetal 
• 99-87-6 4-methylisopropylbenzene 
• 536-59-4 perillol 
• 536-66-3 p-isopropylbenzoic acid 
• 62067-45-2 4-isopropyl cyclohexane carboxylic acid 
• 2111-75-3 perillaldehyde 

Downstream Products

• 46337-76-2 [4-(propane-2-yl)cyclohexyl]methyl acetate 
• 56345-09-6 4-isopropyl-cyclohexylmethyl ethyl ether 
• 67580-45-4 4-isopropylcyclohexyl methyl ketone 
• 63767-86-2 trans-1-(4-isopropylcyclohexyl)-1-ethanol 
• 88166-24-9 4-isopropylcyclohexane-1-carbaldehyde 

Relevant articles and documents

Atomic-layer-deposition-formed sacrificial template for the construction of an MIL-53 shell to increase selectivity of hydrogenation reactions

We developed a method for using atomic layer deposition (ALD)-formed layers of Al2O3 as a sacrificial template to generate MIL-53(Al). The MOF shell in the CeO2/Pd@MIL-53(Al) configuration not only stabilized the Pd nanoparticles, but also regulated the selectivity of the hydrogenation of unsaturated aldehydes. This work represents the first demonstration of ALD-formed layers of metal oxides serving as sacrificial templates in the design of MOF-shell-based sandwich-type structures.

Catalyst and process for hydrogenating aromatics

The present invention relates to an eggshell catalyst comprising an active metal selected from the group consisting of ruthenium, rhodium, palladium, platinum and mixtures thereof, applied to a support material comprising silicon dioxide, wherein the pore volume of the support material is 0.6 to 1.0 ml/g, determined by Hg porosimetry, the BET surface area is 280 to 500 m2/g, and at least 90% of the pores present have a diameter of 6 to 12 nm, to a process for preparing this eggshell catalyst, to a process for hydrogenating an organic compound which comprises at least one hydrogenatable group using the eggshell catalyst, and to the use of the eggshell catalyst for hydrogenating an organic compound.

PROCESS FOR PREPARING 4-ISOPROPYLCYCLOHEXYLMETHANOL

The present invention relates to a process for preparing 4-isopropylcyclohexylmethanol (IPCHM) from para-cymene. The process for preparing 4-isopropylcyclohexylmethanol (IPCHM) comprises an electrochemical process for preparing a mixture of 4-isopropylbenzaldehyde dimethyl acetal and 4-(1-alkoxy-1-methylethyl)benzaldehyde dimethyl acetal, and intermediates passed through in the process, a hydrolysis step to form the corresponding benzaldehydes and a hydrogenation of this mixture to form 4-isopropylcyclohexylmethanol (IPCHM).

Experimental determination of the conformational free energies (A values) of fluorinated substituents in cyclohexane by dynamic 19F NMR spectroscopy. Part 2. Extension to fluoromethyl, difluoromethyl, pentafluoroethyl, trifluoromethylthio and trifluoromethoxy groups

The synthesis of monosubstituted and 1,4-substituted cyclohexanes bearing one of the title groups is described. The conformational analysis of these compounds was studied by 19F NMR spectroscopy at various temperatures. Chemical shifts for each conformer above the coalescence temperature were obtained by binomial regression from low temperature values, allowing the high precision determination of the equilibrium constants, and the corresponding thermodynamic parameters (ΔG°, ΔH°, ΔS°) of the fluorinated substituents. For A values (-ΔG°298K), the following averaged data were obtained: 1.59 (CFH2), 1.85 (CF2H), 2.67 (C2F5), 0.79 (OCF3) and 1.18 (SCF3) [in kcal mol-1]. the Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2006.

Compounds having protected hydroxy groups

The present invention relates to compounds with protected hydroxy groups of formula (I) These compounds are precursors for organoleptic agents, such as fragrances, and masking agents and for antimicrobial agents. When activated, the compounds of formula (I) are cleaved and form one or more organoleptic and/or antimicrobial compounds.

PERFUME COMPOSITION

A perfume composition contains specified ketones, salicylates and alcohols/acetates/propionates. Use of such a perfume composition inhibits development of human body malodour. The combination of specified materials makes it possible to avoid inclusion of individual components with powerful, unacceptable odours. The perfume composition may be used in various products notably in a fabric conditioning product used during the rinsing or tumble drying of fabrics after washing to soften the fabrics.

Perfume compositions

A perfume composition contains at least 50% by weight of materials which fall into five categories defined by structure, and molecular weight. Amounts of material within each category fall within specified ranges of percentage of the whole composition. Two categories, ethers and salicylates, must be present. At least two of the remaining three categories, which are alcohols, acetate/propionate esters and methyl aryl ketones, must also be present. The compositions enable good levels of deodorant activity to be achieved along with consumer-acceptable fragrance.

Deodorant compositions

The invention provides a deodorant composition suitable for topical application to the human skin, comprising a composition of fragrance materials which have a Deodorant Value greater than 0.25, as measured by the Deodorant Value Test, and an inorganic deodorant active material, in a cosmetically suitable vehicle.

Alicyclic compounds, their use and process for preparing same

Use of alicyclic compounds, some of which are new, as odor-modifying ingredients for manufacturing perfumes, perfumed products or synthetic essential oils, and as flavor-modifying ingredients for the manufacture of artificial flavors or for the aromatization of foodstuffs, animal feeds, pharmaceutical preparations or tobacco products. Process for preparing said alicyclic compounds.