55023-86-4Relevant academic research and scientific papers
Reduction of Benzolactams to Isoindoles via an Alkoxide-Catalyzed Hydrosilylation
Ding, Guangni,Wu, Xiaoyu,Jiang, Lili,Zhang, Zhaoguo,Xie, Xiaomin
supporting information, p. 6048 - 6051 (2017/11/24)
An alkoxide-catalyzed reduction of benzolactams to isoindoles with silanes was realized. With t-BuOK as the catalyst and Ph2SiH2 as the reductant, a series of benzolactams containing different functional groups were reduced to the co
Cycloaddition-based formal C-H alkynylation of isoindoles leading to the synthesis of air-stable fluorescent 1,3-dialkynylisoindoles
Ohmura, Toshimichi,Kijima, Akihito,Komori, Yusuke,Suginome, Michinori
supporting information, p. 3510 - 3513 (2013/08/23)
Reaction of N-alkylisoindoles with (bromoethynyl)triisopropylsilane afforded 1,3-bis(triisopropylsilylethynyl) isoindoles in high yields. The formal C-H alkynylation proceeds under transition-metal-free conditions through [4 + 2] cycloaddition of the pyrrole ring of isoindole with bromoalkyne followed by ring-opening of the product.
Integrated catalytic C-H transformations for one-pot synthesis of 1-arylisoindoles from isoindolines via palladium-catalyzed dehydrogenation followed by C-H arylation
Ohmura, Toshimichi,Kijima, Akihito,Suginome, Michinori
supporting information; experimental part, p. 1238 - 1241 (2011/05/03)
A one-pot conversion of isoindolines to 1-arylisoindoles was established from palladium-catalyzed cascade C-H transformations, that is, the dehydrogenation of isoindolines to give isoindoles, with subsequent C-H arylation of the isoindoles.(Figure Presented)
Studies on the Chemistry of Isoindoles and Isoindolenines, XXXVI. - Reactions of 2-Alkyl-2H-isoindoles with Maleic Imides
Kreher, Richard P.,Seubert, Juergen,Schmitt, Dieter,Use, Goetz,Kohl, Norbert,Muleta, Tilahun
, p. 381 - 390 (2007/10/02)
2-Alkyl-2H-isoindoles 2 react with maleic imides 4 exclusively in position 1 and 3 by cycloaddition to form Diels-Alder adducts.The transformation of the endo isomers 6 into the thermodynamically more stable exo isomers 7 depends on the dienophile.The cyc
