304-17-6

Basic information

• Product Name: N-Isopropylphthalimide
• Synonyms: 1H-Isoindole-1,3(2H)-dione,2-(1-methylethyl)-;2-(1-methylethyl)-1h-isoindole-3(2h)-dione;2-Isopropyl-isoindole-1,3-dione;n-isopropilftalimmide;n-isopropylftalimid;n-isopropyl-phthalimid;N-ISOPROPYL PHTHALIMIDE;ISOPROPYLPHTHALIMIDE
• CAS NO: 304-17-6
• Molecular Formula: C₁₁H₁₁NO₂
• Molecular Weight: 189.21
• EINECS: 206-150-5
• Product Categories: Derivatives of phthalimide
• Mol File: 304-17-6.mol
• Article Data: 28

Chemical Properties

• Melting Point: 82-84°C
• Boiling Point: 273°C(lit.)
• Flash Point: 121.1 °C
• Appearance: slight yellow liquid
• Density: 1.1596 (rough estimate)
• Vapor Pressure: 0.00253mmHg at 25°C
• Refractive Index: 1.5012 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -2.15±0.20(Predicted)
• CAS DataBase Reference: N-Isopropylphthalimide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Isopropylphthalimide(304-17-6)
• EPA Substance Registry System: N-Isopropylphthalimide(304-17-6)

Safety Data

• RTECS: TI5425000
• Hazardous Substances Data: 304-17-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H11NO2/c1-7(2)12-10(13)8-5-3-4-6-9(8)11(12)14/h3-7H,1-2H3

Upstream product

• 1914-20-1 N-methoxyphthalimide 
• 75-31-0 isopropylamine 
• 136918-14-4 phthalimide 
• 67-63-0 isopropyl alcohol 
• 75-30-9 2-iodo-propane 
• 88-95-9 Phthaloyl dichloride 
• 5440-69-7 N-isopropylbenzamide 
• 201230-82-2 carbon monoxide 
• 98-88-4 benzoyl chloride 
• 65-85-0 benzoic acid 
• 598-45-8 i-propyl isocyanide 
• 124-38-9 carbon dioxide 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 3481-09-2 N-chlorophthalimide 

Downstream Products

• 75-31-0 isopropylamine 
• 5440-69-7 N-isopropylbenzamide 
• 65399-00-0 2,3-dihydro-2-(1-methylethyl)-1H-isoindol-1-one 
• 55023-86-4 2-Isopropyl-2H-isoindol 
• 1265964-66-6 2-isopropyl-1-phenyisoindole 
• 1265964-63-3 2-isopropyl-1,3-diphenyisoindole 
• 32003-14-8 4-benzyl-2H-phthalazin-1-one 

Relevant articles and documents

Wavelength dependent photoextrusion and tandem photo-extrusion reactions of ninhydrin bis-acetals for the synthesis of 8-ring lactones, benzocyclobutenes and orthoanhydrides

Ninhydrin bis-acetals give access to 8-ring lactones, benzocyclo-butenes and spirocyclic orthoanhydrides through photoextrusion and tandem photoextrusion reactions. Syntheses of fimbricalyxlactone B, isoshihunine and numerous biologically-relevant heteroc

Method for constructing N-isopropylphthalimide in one step by using imine as starting material

The invention discloses a method for constructing N-isopropylphthalimide in one step by using imine as a starting material. According to the method, (E)-N-isopropyl-1-phenylmethylenimine is used as areaction raw material and subjected to a carbonylation reaction to construct N-isopropylphthalimide in one step. The method has the characteristics of mild reaction conditions, simple operation procedures and excellent yield.

Method for synthesizing N-isopropylphthalimide

The invention discloses a method for synthesizing N-isopropylphthalimide. Phthalimide and propylene used as main reaction substrates undergo a nucleophilic addition reaction under the catalysis of a catalyst at a reaction temperature of 50-200 DEG C for 1-30 h to obtain the N-isopropylphthalimide, wherein a molar ratio of phthalimide to propylene in the reaction system is 1:1 to 1:10. The phthalimide and propylene used in the method are all cheap and easily-available raw materials, and the method also has the advantages of mild reaction conditions, no byproducts in the process, high conversionrate and low production cost. The content of normal bodies can reach 98% or more.