55028-76-7Relevant academic research and scientific papers
Synthesis and cytotoxic effect of pseudodiosgenyl saponins with thio-ring F
Zan, Xin,Gao, Jian,Gu, Guofeng,Liu, Shanshan,Sun, Bin,Liu, Lei,Lou, Hong-Xiang
supporting information, p. 1600 - 1604 (2014/03/21)
Both the sugar moieties and aglycons of steroid saponins play important roles for their bioactivities. In order to test the biological contribution of the glycosyl residue and search new saponins with notable anticancer activity, mono- and di-saccharide p
Convergent synthesis and cytotoxic activities of 26-thio- and selenodioscin
Chen, Pengwei,Wang, Peng,Song, Ni,Li, Ming
, p. 959 - 966 (2013/11/06)
Convergent block syntheses of 26-thio- and selenodioscin have been achieved by developing the highly stereoselective 1,2-trans glycosylations of chacotriosyl imidate without recourse to neighboring group assistance. Both thiodioscin and selenodioscin possess cytotoxic activities similar to dioscin, a natural spirostanol glycoside.
Preparations of heterospirostanols and their pharmacological activities
Quan, Hang-Ji,Koyanagi, Jyunichi,Ohmori, Koichi,Uesato, Shinichi,Tsuchido, Tetsuaki,Saito, Setsuo
, p. 659 - 669 (2007/10/03)
(3β,20S,22S,25R)-22-Thiospirosol-5-en-3-ol (9) and (3β,20S,22S,25R)-22-seleno-spirosol-5-en-3-ol (11) were prepared from diosgenin (3) via 26-iodopseudodiosgenin (6) as a key intermediate. Diosgenone (15), solasodinone (16), (20S,22S,25R)-22-thio-spirosol
