6808-14-6

Basic information

• Product Name: (25R)-Furosta-5,20(22)-diene-3β,26-diol
• Synonyms: (25R)-Furosta-5,20(22)-diene-3β,26-diol;Pseudodiosgenin
• CAS NO: 6808-14-6
• Molecular Formula: C₂₇H₄₂O₃
• Molecular Weight: 414.62058
• Mol File: 6808-14-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (25R)-Furosta-5,20(22)-diene-3β,26-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (25R)-Furosta-5,20(22)-diene-3β,26-diol(6808-14-6)
• EPA Substance Registry System: (25R)-Furosta-5,20(22)-diene-3β,26-diol(6808-14-6)

Safety Data

• Hazardous Substances Data: 6808-14-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(25R)-Furosta-5,20(22)-diene-3β,26-diol is used as a pharmaceutical precursor for the development of new drugs, leveraging its anti-inflammatory, immunomodulatory, and anticancer properties. Its potential to lower cholesterol levels and improve cardiovascular health also makes it a candidate for the treatment of related conditions.
Used in Nutraceutical Industry:
As a natural steroid precursor, (25R)-Furosta-5,20(22)-diene-3β,26-diol can be used as an ingredient in nutraceutical products aimed at promoting overall health and well-being, particularly in the areas of inflammation management and cardiovascular health.
Used in Cosmetic Industry:
Due to its potential anti-inflammatory and immunomodulatory effects, (25R)-Furosta-5,20(22)-diene-3β,26-diol may be utilized in cosmetic products designed to improve skin health and address issues related to inflammation and immune response in the skin.
Used in Research and Development:
(25R)-Furosta-5,20(22)-diene-3β,26-diol serves as a valuable compound in research and development for the discovery of new therapeutic agents and understanding its full range of biological activities, which could lead to novel applications in medicine and healthcare.

Upstream product

• 122190-71-0 (25R)-3β-acetoxy-26-benzoyloxy-furosta-5,20(22)-diene 
• 512-04-9 diosgenin 
• 64-17-5 ethanol 
• 65682-56-6 (25R)-furosta-5,16,20(22)-triene-3β,26-diol 
• 141-78-6 ethyl acetate 
• 122273-19-2 (25R)-3β-acetoxy-26-butyryloxy-furosta-5,20(22)-diene 
• 7604-96-8 C₂₉H₄₄O₄ 
• 2309-38-8 pseudodiosgenin diacetate 
• 470-05-3 (3β,20R,22R,25R)-spirosol-5-en-3-ol 

Downstream Products

• 1573153-97-5 C₄₁H₅₄O₇S₂ 
• 991-62-8 (3b,25R)-3-hydroxyfurosta-5,20⁽²²⁾-dien-26-yl 4-Methylbenzenesulfonate 
• 55028-76-7 (3β,20S,22S,25R)-22-thiospirosol-5-en-3-ol 
• 512-04-9 diosgenin 
• 470-05-3 (3β,20R,22R,25R)-spirosol-5-en-3-ol 
• 93176-77-3 3,26-dimethoxy-23-(p-dimethylaminobenzylidenyl)-furost-5,20-diene 

Relevant articles and documents

Synthesis and cytotoxic effect of pseudodiosgenyl saponins with thio-ring F

Both the sugar moieties and aglycons of steroid saponins play important roles for their bioactivities. In order to test the biological contribution of the glycosyl residue and search new saponins with notable anticancer activity, mono- and di-saccharide p

Synthesis and cytotoxicities of icogenin analogues with disaccharide residues

For further structure-activity relationships (SAR) research of furostan saponin, two icogenin analogues: (25R)-22-O-methyl-furost-5-en-3β,26-diol-3-O-α-l-rhamnopyrano syl-(1 → 2)-β-d-glucopyranoside 1 and (25R)-22-O-methyl-furost-5-en-3β,26-diol-3-O-α-l-r

KHSO4-SiO2-MeOH An efficient selective solid-supported system for deprotection of alcohols from esters

KHSO4-SiO2 can efficiently deprotect alcohols from esters through transesterification in methanol under mild condition. Esters of aromatic alcohols are easily transesterified at room temperature compared to the corresponding aliphatic or alicyclic alcohol. NAcetyl compounds and ethers are resistant to the reagent under the above condition. The method is very useful for preparation of biodiesel methyl ricinoleate from castor oil.

Spirostanols obtained by cyclization of pseudosaponin derivatives and comparison of anti-platelet agglutination activities of spirostanol glycosides

Naturally occurring saponins 3 and 4 have a normal type F ring and α- arranged CH3-21 group. Treatments of pseudosaponin peracetates 18 and 19 derived from 3 and 4, respectively, with alcoholic KOH, followed by acidification with acetic acid, gave spirostanols 20 and 22 having iso type F rings as major products. Structural analyses of sapogenins and saponins derived from pseudo derivatives 11, 12, 18 and 19 were performed by comparisons of their 1H-NMR spectral data and the X-ray analytical data of 3-O-p-bromobenzoyl sarsasapogenin 7, 3-O-acetyl diosgenin 13 and saponin 20. The mechanisms of ring-closure reaction of the side chain at C-22 of pseudosapogenins and pseudosaponins were deduced using stereomodels of the spirostanols derived from 11 under various reaction conditions. Inhibitory activities of saponin diglycosides 3, 4, 20, 21 and 25 on human platelet agglutinations induced by ADP and ristocetin were compared. (C) 2000 Editions scientifiques et medicales Elsevier SAS.