550310-34-4Relevant academic research and scientific papers
Replacement of BF4- by PF6- makes Selectfluor greener
Jin, Zhuang,Xu, Bo,Hammond, Gerald B.,Dimagno, Stephen G.
, p. 226 - 230,5 (2020/08/20)
A combination of F-TEDA-PF6 and CuBr (0.1 equiv.) provides a potent oxidant that readily oxidizes amides to provide imides at room temperature. Replacement of BF4-, the anion of Selectfluor (F-TEDA-BF4), by PF6-, dramatically reduces CuBr loading in this oxidative reaction. A possible rationale for this dramatic counterion effect is provided.
Copper mediated oxidation of amides to imides by Selectfluor
Jin, Zhuang,Xu, Bo,Hammond, Gerald B.
, p. 1956 - 1959 (2011/04/25)
The combination of Selectfluor and copper(I) bromide has shown a strong oxidation ability, readily oxidizing amides into the corresponding imides in acetonitrile at room temperature in less than 1 h. This transformation under mild conditions gives good to excellent chemical yields. A possible reaction mechanism is proposed.
