550346-18-4 Usage
Uses
Used in Pharmaceutical Industry:
2-Acetamido-3-fluorobenzoic acid is used as a chemical intermediate for the synthesis of various pharmaceuticals, leveraging its structural attributes to contribute to the development of drugs with a broad spectrum of therapeutic applications. Its presence in the molecular framework of these compounds can influence their pharmacokinetics, pharmacodynamics, and overall efficacy.
Used in Organic Synthesis:
In the field of organic synthesis, 2-Acetamido-3-fluorobenzoic acid is utilized as a building block for creating a diverse array of organic compounds. Its reactivity and functional groups make it a suitable candidate for various synthetic pathways, leading to the formation of complex molecules with specific properties and applications.
Used in Drug Development:
2-Acetamido-3-fluorobenzoic acid is employed in drug development as a precursor to potential therapeutic agents. Its unique combination of functional groups allows for the design of molecules with targeted biological activities, making it a promising component in the creation of new drugs for treating a variety of diseases and conditions.
Overall, 2-Acetamido-3-fluorobenzoic acid is an important chemical with a wide range of applications across different industries, particularly in the development of pharmaceuticals and organic compounds, where its distinctive structure and properties are harnessed to create innovative and effective products.
Check Digit Verification of cas no
The CAS Registry Mumber 550346-18-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,0,3,4 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 550346-18:
(8*5)+(7*5)+(6*0)+(5*3)+(4*4)+(3*6)+(2*1)+(1*8)=134
134 % 10 = 4
So 550346-18-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H8FNO3/c1-5(12)11-8-6(9(13)14)3-2-4-7(8)10/h2-4H,1H3,(H,11,12)(H,13,14)
550346-18-4Relevant academic research and scientific papers
Palladium-catalyzed C-H bond carboxylation of acetanilides: An efficient usage of N,N-dimethyloxamic acid as the carboxylate source
Wu, Yinuo,Jiang, Cheng,Wu, Deyan,Gu, Qiong,Luo, Zhang-Yi,Luo, Hai-Bin
supporting information, p. 1286 - 1289 (2016/01/15)
N,N-Dimethyloxamic acid can be successfully employed as a carboxylate precursor in the palladium-catalyzed direct C-H carboxylation of acetanilides. The reaction proceeds smoothly under mild conditions over a broad range of substrates with high functional group tolerance, affording substituted N-acyl anthranilic acids in moderate to high yields.
A metal-free approach for transamidation of amides with amines in aqueous media
Srinivas, Mahesuni,Hudwekar, Abhinandan D.,Venkateswarlu, Vunnam,Reddy, G. Lakshma,Kumar, K. A. Aravinda,Vishwakarma, Ram A.,Sawant, Sanghapal D.
supporting information, p. 4775 - 4779 (2015/07/20)
An efficient, environmentally benign and a mild protocol for transamidation of amides with a variety of amines in the presence of K2S2O8 using stoichiometric quantity in aqueous conditions has been established. This method works under conventional thermal conditions and in microwave irradiation as well. A series of amides have been prepared using this reaction and this is a greener protocol for transamidation, which offers a diverse kind of substrate scope with exclusive product formation (yields 90-98%).
