550346-73-1Relevant academic research and scientific papers
Desymmetrisation of cyclopentadienylsilane by asymmetric cyclopropanation
Allais, Florent,Angelaud, Remy,Camuzat-Dedenis, Boris,Julienne, Karine,Landais, Yannick
, p. 1069 - 1073 (2003)
Desymmetrisation of silylcyclopenta-2,4-diene was carried out by an asymmetric copper(I)-mediated cyclopropanation. An in-depth investigation with various ligands led to the discovery that the PyBox ligands 10a-c were the most efficient ligands for this transformation and led to the cyclopropane 7a with an ee of up to 72%. Further studies aimed at providing insights into the origin of this enantiocontrol are also provided. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
