550366-51-3Relevant academic research and scientific papers
Improving resins for solid phase synthesis: Incorporation of 1-[2-(2-methoxyethoxy)ethoxy]-4-vinyl-benzene
Alesso, Sonia M.,Yu, Zhanru,Pears, David,Worthington, Paul A.,Luke, Richard W. A.,Bradley, Mark
, p. 7163 - 7169 (2003)
The preparation, characterisation and application of a series of non-grafted polystyrene (PS) resins containing a styrenic methoxypoly(ethylene glycol) (MPEG) derivative is presented. These novel PS-MPEG resins were designed to balance swelling and solvation with improved handling. The monomer, 1-[2-(2-methoxyethoxy)ethoxy]-4-vinyl-benzene, contained an inert phenyl ether linkage designed to provide broad chemical compatibility and stability, yet imparting all the favourable properties of the PEG group into the new resin, whilst maintaining a high loading capacity. The synthetic performance of the new resins compared very favourably to those of TentaGel, ArgoGel and aminomethyl PS.
