550378-39-7 Usage
Uses
Used in Pharmaceutical Industry:
(S)-1-Cbz-3-Aminopyrrolidine hydrochloride is used as a chiral building block for the synthesis of various pharmaceuticals and biologically active compounds. Its unique structure and properties enable the development of innovative drugs with improved efficacy and selectivity.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (S)-1-Cbz-3-Aminopyrrolidine hydrochloride is employed as a key intermediate in the synthesis of complex organic molecules. Its versatility allows researchers to explore new chemical pathways and develop novel therapeutic agents.
Used in Drug Development:
(S)-1-Cbz-3-Aminopyrrolidine hydrochloride plays a crucial role in drug development, as it serves as a precursor for the synthesis of potential drug candidates. Its stable and water-soluble hydrochloride form makes it an ideal candidate for further chemical modifications and optimization to enhance the pharmacological properties of the resulting compounds.
Used in Organic Synthesis:
As a key intermediate in organic synthesis, (S)-1-Cbz-3-Aminopyrrolidine hydrochloride is utilized in the preparation of a wide range of organic compounds. Its unique structure and reactivity make it a valuable building block for the synthesis of complex molecules with diverse applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 550378-39-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,0,3,7 and 8 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 550378-39:
(8*5)+(7*5)+(6*0)+(5*3)+(4*7)+(3*8)+(2*3)+(1*9)=157
157 % 10 = 7
So 550378-39-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H16N2O2.ClH/c13-11-6-7-14(8-11)12(15)16-9-10-4-2-1-3-5-10;/h1-5,11H,6-9,13H2;1H/t11-;/m0./s1
550378-39-7Relevant academic research and scientific papers
Discovery of aminopiperidine-based Smac mimetics as IAP antagonists
Hennessy, Edward J.,Saeh, Jamal C.,Sha, Li,MacIntyre, Terry,Wang, Haiyun,Larsen, Nicholas A.,Aquila, Brian M.,Ferguson, Andrew D.,Laing, Naomi M.,Omer, Charles A.
, p. 1690 - 1694 (2012/04/10)
A series of structurally unique Smac mimetics that act as antagonists of inhibitor of apoptosis proteins (IAPs) has been discovered. While most previously described Smac mimetics contain the proline ring (or a similar cyclic motif) found in Smac, a key feature of the compounds described herein is that this ring has been removed. Despite this, compounds in this series potently bind to cIAP1 and elicit the expected phenotype of cIAP1 inhibition in cancer cells. Marked selectivity for cIAP1 over XIAP is observed for these compounds, which is attributed to a slight difference in the binding groove between the two proteins and the resulting steric interactions with the inhibitors. XIAP binding can be improved by constraining the inhibitor so that these unfavorable steric interactions are minimized.
Antithrombotic agents
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Page/Page column 13; 17, (2010/02/05)
This application relates to a compound of formula I (or a prodrug thereof or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well a
