55049-01-9Relevant academic research and scientific papers
First chemical synthesis of three natural depsides involved in flavonol catabolism and related to quercetinase catalysis
Tranchimand, Sylvain,Tron, Thierry,Gaudin, Christian,Iacazio, Gilles
, p. 587 - 597 (2006)
We report here the first chemical synthesis of three depsides related to quercetinase-catalyzed degradation of kaempferol, quercetin, and myricetin. The three depsides were constructed through the coupling of suitably protected phloroglucinol carboxylic acid and hydroxy-perbenzylated, derivatives of gallic, protocatechuic, and 4-hydroxy benzoic acids. The three synthesized target compounds proved to be identical to their natural counterparts, arising from quercetinase action on corresponding flavonols. Copyright Taylor & Francis Group, LLC.
