55070-01-4

Usage

InChI:InChI=1/C23H31N3O6/c1-13(2)19-22(29)26-18(8-6-7-16-9-11-17(31-5)12-10-16)21(28)24-14(3)20(27)25-15(4)23(30)32-19/h9-13,15,18-19H,3,6-8H2,1-2,4-5H3,(H,24,28)(H,25,27)(H,26,29)/t15-,18-,19-/m0/s1

Upstream product

• 178861-43-3 (3S,6S,9S,12S)-12-Isopropyl-9-[3-(4-methoxy-phenyl)-propyl]-3-methyl-6-phenylselanylmethyl-1-oxa-4,7,10-triaza-cyclododecane-2,5,8,11-tetraone 
• 17407-55-5 (S)-2-Hydroxy-3-methylbutanoic acid 
• 2441-07-8 benzyl (R)-2-hydroxy-3-methylbutanoate 
• 5406-18-8 3-(p-methoxyphenyl)-1-propanol 
• 1929-29-9 3-(4-methoxyphenyl)propanoic acid 
• 62732-50-7 2-Acetylamino-2-[3-(4-methoxy-phenyl)-propyl]-malonic acid diethyl ester 
• 62732-53-0 2-Acetylamino-2-[3-(4-methoxy-phenyl)-propyl]-malonic acid 
• 112037-13-5 (R)-2-((R)-2-tert-Butoxycarbonylamino-propionyloxy)-3-methyl-butyric acid benzyl ester 
• 112037-07-7 (R)-2-((R)-2-tert-Butoxycarbonylamino-propionyloxy)-3-methyl-butyric acid 
• 178861-41-1 (S)-2-{(S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenylselanyl-propionylamino)-propionyloxy]-3-methyl-butyrylamino}-5-(4-methoxy-phenyl)-pentanoic acid tert-butyl ester 
• 178861-39-7 (S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-propionyloxy)-3-methyl-butyrylamino]-5-(4-methoxy-phenyl)-pentanoic acid tert-butyl ester 
• 178861-45-5 Boc-L-Amp-O-tBu 

Relevant academic research and scientific papers

Facile Syntheses of AM-toxins and Analogs as Cyclic Depsipeptides by the Solid-phase Method

The cyclic depsipeptides, AM-toxins I and II and AM-toxin I analogs, were efficiently and rapidly prepared by the Fmoc-based solid-phase method for the synthesis of linear depsipeptides, with N-pyridin-1-ylmethylene>-N-methylmethanaminium hexafluorophosphate N-oxide (HATU) being used for their subsequent cyclization. - Keywords: Am-toxin; host-specific toxin; cyclic depsipeptide; solid-phase synthesis; HATU.

β-Phenylselenoalanine as a dehydroalanine precursor-efficient synthesis of alternariolide (AM-toxin I)

Alternariolide (AM-toxin) is synthesized in 44% overall yield from L-2-amino-5-(4-methoxyphenyl)pentanoic acid; D-β-phenylselenoalanine is used as the dehydroalanine precursor.