55079-14-6

Basic information

• Product Name: 2-(4-methoxybenzylidene)-1-(2-methyl-7-ethoxyquinolin-4-yl)hydrazine
• CAS NO: 55079-14-6
• Molecular Weight: 335.406
• Mol File: 55079-14-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxybenzylidene)-1-(2-methyl-7-ethoxyquinolin-4-yl)hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxybenzylidene)-1-(2-methyl-7-ethoxyquinolin-4-yl)hydrazine(55079-14-6)
• EPA Substance Registry System: 2-(4-methoxybenzylidene)-1-(2-methyl-7-ethoxyquinolin-4-yl)hydrazine(55079-14-6)

Safety Data

• Hazardous Substances Data: 55079-14-6(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 344561-79-1 (7-Ethoxy-2-methyl-quinolin-4-yl)-hydrazine 

Relevant articles and documents

Development of antitubercular compounds based on a 4-quinolylhydrazone scaffold. Further structure-activity relationship studies

A series of 4-quinolylhydrazones was synthesized and tested in vitro against Mycobacterium tuberculosis. At a concentration of 6.25 μg/mL, most of the newly synthesized compounds displayed 100% inhibitory activity against M. tuberculosis in cellular assays. Further screening allowed the identification of very potent antitubercular agents. Compound 4c was also tested in a time-course experiment and against mtb clinical isolates, displaying interesting results.