5509-89-7Relevant academic research and scientific papers
Substitution Reactions of Phenylated Aza-heterocycles. Part 1. Nitration of 2,5-Diphenyl-1,3,4-oxadiazole: a Product Study using High Performance Liquid Chromatography
Blackhall, Alexander,Brydon, Donald L.,Saga, Anthony J. G.,Smith, David M.
, p. 773 - 777 (2007/10/02)
Contrary to a previous literature report, nitration of 2,5-diphenyl-1,3,4-oxadiazole (1) under various conditions gives a mixture of all six possible 2,5-bisnitrophenyl derivatives, which may be analysed quantitatively using high performance liquid chromatography.Nitration using nitric acid alone gives mainly the three isomers with p-nitrophenyl groups, i.e. (7), (9), and (10), whereas mixed acids and nitronium tetrafluoroborate give mainly meta-nitration products, i.e. (6), (8), and (9).Nitration of the three 2-(nitrophenyl)-5-phenyl-1,3,4-oxadiazoles also shows considerable variation of product ratio according to the conditions.
Oxidation of Aroyl Hydrazines: Part X - Kinetics of Oxidation of Benzoyl Hydrazines by Chloramine-T in Alkaline Medium
Ramaiah, A. Kodanda,Rao, P. V. Krishna
, p. 1120 - 1122 (2007/10/02)
The kinetics of oxidation of benzoyl hydrazines by chloramine-T (CAT) in aq. methanol medium in the pH range 8.9-11.5 has been investigated.The order of reaction with respect to the oxidant and substrate is one each.The rate is found to be independent of pH.The reaction is accelerated by electron withdrawing groups and retarded by electron releasing groups, with a ρ value of + 0.80.An increase in the dielectric constant of the medium increases the rate whereas the ionic strength has no significant effect.A suitable mechanism has been suggested.
