55106-53-1

Usage

Chemical structure

1-Bromocyclohexanecarboxylic acid is an organic compound that contains a cyclohexane ring with a carboxylic acid group and a bromine substituent.

Functional groups

The compound has two main functional groups a carboxylic acid group and a bromine atom.

Reactivity

The bromine atom provides the compound with reactivity and can be used as a leaving group in substitution reactions.

Carboxylic acid group

The carboxylic acid group also provides reactivity, as it can undergo reactions such as esterification and amidation.

Applications

1-Bromocyclohexanecarboxylic acid is used in the synthesis of various organic compounds and pharmaceuticals.

Versatility

The compound is versatile with applications in organic synthesis and drug development.

Physical properties

The specific physical properties of 1-bromocyclohexanecarboxylic acid, such as melting point, boiling point, and solubility, are not provided in the material.

Chemical properties

The specific chemical properties of 1-bromocyclohexanecarboxylic acid, such as its reactivity with other compounds and its stability under different conditions, are not provided in the material.

Upstream product

• 2719-27-9 cyclohexanylcarbonyl chloride 
• 98-89-5 Cyclohexanecarboxylic acid 
• 55106-50-8 (1-Bromo-cyclohexyl)-oxo-acetonitrile 
• 108-94-1 cyclohexanone 
• 3252-43-5 dibromoacetonitrile 
• 75-25-2 Bromoform 

Downstream Products

• 636-82-8 cyclohexene-1-carboxylic acid 
• 874164-33-7 1-bromo-cyclohexanecarboxylic acid methyl-pyridin-4-yl-amide 
• 1415959-03-3 1-benzyl-3-(4-methoxyphenyl)-1,3-diazaspiro[4.5]decane-2,4-dione 
• 1415959-04-4 benzyl 4-(1-benzyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)-phenylcarbamate 
• 92357-91-0 1,3-dibenzyl-1,3-diazaspiro[4.5]decane-2,4-dione 
• 1415959-00-0 1-benzyl-3-tert-butyl-1,3-diazaspiro[4.5]decane-2,4-dione 
• 1415959-11-3 1-bromo-N-phenyl-N-(phenylcarbamoyl)cyclohexanecarboxamide 
• 1415958-92-7 1,3-dicyclohexyl-1,3-diazaspiro[4.5]decane-2,4-dione 
• 1415959-09-9 1-bromo-N-cyclohexyl-N-(cyclohexylcarbamoyl)cyclohexane-carboxamide 

Relevant academic research and scientific papers

Cobalt-Catalyzed 1,4-Aryl Migration/Desulfonylation Cascade: Synthesis of α-Aryl Amides

A cobalt-catalyzed 1,4-aryl migration/disulfonylation cascade applied to α-bromo N-sulfonyl amides was developed. The reaction was highly chemoselective, allowing the preparation of α-aryl amides possessing a variety of functional groups. The method was used as the key step to synthesize an alkaloid, (±)-deoxyeseroline. Mechanistic investigations suggest a radical process.

Synthesis of Hindered α-Amino Carbonyls: Copper-Catalyzed Radical Addition with Nitroso Compounds

The synthesis of sterically hindered anilines has been a significant challenge in organic chemistry. Here we report a Cu-catalyzed radical addition with in situ-generated nitroso compounds to prepare sterically hindered amines directly from readily available materials. The transformation is conducted at room temperature, uses abundant copper salts, and is tolerant of a range of functional groups.

One-step conversion of ketones to conjugated acids using bromoform

Phase-transfer-catalyzed (PTC) reactions of ketones with bromoform and aqueous lithium hydroxide in alcoholic solvent result in the formation of ,-unsaturated carboxylic acids. The reaction was performed at room temperature for 24h. The corresponding conj

Facile synthesis of 3,3-dialkyl-6-phenyl-imidazopyridinones

A series of novel 3,3-dialkylated imidazopyridinones bearing 6-aryl groups were designed as mimetics of active progesterone antagonists, 3,3-disubstituted-5-arylindoles. The four-step synthetic route is described. The key steps are base-catalyzed cyclizat

Homolytic aromatic substitution: A radical approach towards the synthesis of 5-azaoxindoles

A range of 5-azaoxindoles have been synthesised employing homolytic aromatic substitution onto pyridine as the pivotal step.

6-(Substituted-cycloalkylcarboxamide) penicillanic acids

Penicillins of the formula SPC1 Or a pharmaceutically-acceptable, nontoxic salt thereof, Wherein R1 and R2 are the same or different and each is hydrogen, fluorine, chlorine or bromine; or when R2 is hydrogen, R1 can also be cyano, hydroxyl, azido, amino or nitro; or R1 and R2 are bonded to a ring carbon atom and constitute a single oxygen atom; R3 is hydrogen, methyl, chlorine, bromine, cyano, methoxy or carboxyl; and n is 2 to 7; Are useful for their antibacterial activity.