55111-68-7

Usage

Thiazolidine derivative

A class of compounds known for their various biological activities.

Potential pharmacological properties

Studied for its anti-inflammatory and anti-tumor effects.

Molecular structure

Contains a thiazolidine ring with a thioxo group and a phenyl and chlorobenzylidene substituent.

Biological activity contribution

The phenyl and chlorobenzylidene substituent are believed to contribute to its biological activity.

Further research needed

More research and studies are required to fully understand its potential applications and uses.

Upstream product

• 98949-09-8 5-chloromethylene-3-phenyl-2-thioxo-thiazolidin-4-one 
• 108-90-7 chlorobenzene 
• 1457-46-1 3-phenylrhodanine 
• 104-88-1 4-chlorobenzaldehyde 
• 3747-07-7 5-ethoxymethylene-3-phenyl-2-thioxo-thiazolidin-4-one 

Downstream Products

• 473713-30-3 7-(4-chloro-phenyl)-4-phenyl-2,6-dithia-4-aza-bicyclo[3.2.0]hept-1⁽⁵⁾-ene-3-thione 
• 102546-47-4 5-(4-chloro-4'-methyl-benzhydryl)-3-phenyl-2-thioxo-thiazolidin-4-one 
• 102467-75-4 5-(4-chloro-benzhydryl)-3-phenyl-2-thioxo-thiazolidin-4-one 

Relevant academic research and scientific papers

A convenient synthesis of 3,5-diarylthieto[2,3-d]thiazole-2-thiones, and expansion of their thiete ring with carbon disulphide

3-Aryl-5-arylidenerhodanines 3a-f react with 0,0-diethyl hydrogen phosphorodithioate 4 to yield 3,5-diarylthieto[2,3-d]thiazole-2-thiones 6a-f in a one-pot procedure. The compounds 6a-f undergo expansion of their thiete ring by the reaction with carbon disulphide, catalysed by lithium iodide, to afford the corresponding 3,7-diarylthiazolo[4,5-d]-1,3-dithiin-2,5-dithiones 7a-f in high yields under mild conditions.

Synthesis and insecticidal activity of 5-amino-7-aryl-6-cyano-3-substituted-thiazolo-2,3,4,7-tetrahydropyridine-2-thione and 7-aryl-6-cyano-3-substituted-2-thioxo-thiazolo-2,3,4,5,6,7-hexahydropyridin-5-one

5-Amino-7-aryl-6-cyano-3-substituted-thiazolo-2,3,4,7-tetrahydropyridine-2-thione 3 and 7-aryl-6-cyano-3-substituted-2-thioxo-thiazolo-2,3,4,5,6,7-hexahydropyridin-5-one 4 have been prepared by Michael addition between α,β-unsaturated ketone