55114-29-9

Usage

Uses

Used in the Food Industry:
DIETHYL (2-PENTYL)MALONATE, 98 is used as a flavoring agent to impart a pleasant aroma and taste to a variety of food products, enhancing their sensory appeal to consumers.
Used in the Chemical Synthesis Industry:
DIETHYL (2-PENTYL)MALONATE, 98 is employed in the synthesis of other organic compounds, contributing to the creation of new chemical entities with potential applications in various fields.
Used as a Reagent in Chemical Reactions:
In the realm of chemical research and development, DIETHYL (2-PENTYL)MALONATE, 98 serves as a reagent, facilitating specific chemical reactions and processes that are essential for the advancement of chemical science and technology.
It is crucial to handle and store DIETHYL (2-PENTYL)MALONATE, 98 with care, adhering to proper safety and handling procedures to mitigate any potential hazards associated with its use.

InChI:InChI=1/C12H22O4/c1-5-8-9-12(4,10(13)15-6-2)11(14)16-7-3/h5-9H2,1-4H3

Upstream product

• 542-69-8 1-iodo-butane 
• 18424-77-6 sodium diethyl methylmalonate 
• 106-98-9 1-butylene 
• 62116-54-5 sodium diethyl methylmalonate 
• 77958-43-1 diethyl (pentachlorobutadienyl)methylmalonate 
• 609-08-5 Diethyl methylmalonate 
• 74-88-4 methyl iodide 
• 133-08-4 diethyl butylmalonate 
• 109-65-9 1-bromo-butane 

Downstream Products

• 291773-90-5 1-benzyl-4-butyl-4-methylpyrazolidine-3,5-dione 
• 291774-22-6 4'-(2,4-dibutyl-4-methyl-3,5-dioxo-pyrazolidin-1-ylmethyl)-biphenyl-2-sulfonic acid amide 
• 291774-17-9 1,4-dibutyl-2-[[2'-(N-tert-butylaminosulfonyl)(1,1'-biphenyl)-4-yl]methyl]-4-methylpyrazolidine-3,5-dione 
• 1188414-55-2 Toluene-4-sulfonic acid 2-methyl-hexyl ester 
• 17001-24-0 12-methylhexadecanoic acid 
• 101258-57-5 1-bromo-2-methylhexane 
• 4536-23-6 2-methylhexanoic acid 
• 624-22-6 2-methylhexan-1-ol 

Relevant academic research and scientific papers

Syntheses of female sex pheromone precursors of pine sawfly species and of some structurally related methyl-branched long-chain 2-alkanols.

3,7-Dimethyl-2-undecanol, 3,7,9-trimethyl-2-tridecanol, and 3,7, 11-trimethyl-2-tridecanol were synthesized as racemic mixtures in moderate yields. The alcohols are known precursors of the female sex pheromones of the pine sawfly species Diprion nipponica, Macrodiprion nemoralis, and Microdiprion pallipes, respectively. Stereoisomeric mixtures of 3,8,12-trimethyl-2-tridecanol, erythro-(2R,3R, 11R/S)-3,11-dimethyl-2-tetradecanol, 3,5-dimethyl-2-tetradecanol, and 5,7-dimethyl-2-tetradecanol, structurally related to sex pheromone alcohol precursors of pine sawfly species, were also synthesized in moderate yields. The key reaction in the syntheses was the ring opening of gamma-butyrolactones by using different alkyl lithiums as nucleophiles.

Synthesis and pharmacological evaluation of new pyrazolidine-3,5-diones as AT1 angiotensin II receptor antagonists

On the basis of the structure of the non-peptide receptor antagonist irbesartan, a new series of AT1 ligands was designed. In these compounds the central imidazolone nucleus of irbesartan was replaced by a pyrazolidine-3,5-dione structure. The key intermediate N-alkylpyrazolidine-3,5-diones were synthesized according to a new and general method. The most active compounds possess a spirocyclopentane ring at position 4, a linear butyl chain at position 1, and the [2'(5-tetrazolyl)biphenyl-4- yl]methyl or [2'-(benzoylaminosulfonyl)biphenyl-4-yl]methyl group at position 2. Affinity toward the AT1 and AT2 receptors was assessed by the ability of the compounds to competitively displace [3H]AII from its specific binding sites. The most active compounds, 28 and 48, displayed high affinity for the AT1 receptor, good selectivity AT1 versus AT2, and potent in vitro antagonist activity.