55116-57-9Relevant academic research and scientific papers
Convenient synthesis of benziodazolone: New reagents for direct esterification of alcohols and amidation of amines
Postnikov, Pavel S.,Rohde, Gregory T.,Saito, Akio,Shea, Michael T.,Vlasenko, Yulia A.,Yoshimura, Akira,Yusubov, Mekhman S.,Zhdankin, Viktor V.
, (2021/12/17)
Hypervalent iodine heterocycles represent one of the important classes of hypervalent iodine reagents with many applications in organic synthesis. This paper reports a simple and convenient synthesis of benziodazolones by the reaction of readily available iodobenzamides with m-chloroperoxybenzoic acid in acetonitrile at room temperature. The structure of one of these new iodine heterocycles was confirmed by X-ray analysis. In combination with PPh3 and pyridine, these benziodazolones can smoothly react with alcohols or amines to produce the corresponding esters or amides of 3-chlorobenzoic acid, respectively. It was found that the novel benziodazolone reagent reacts more efficiently than the analogous benziodoxolone reagent in this esterification.
Preparation method of acifluorfen
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Paragraph 0051, (2016/10/27)
The invention relates to the field of herbicides and specifically discloses a preparation method of acifluorfen. The acifluorfen is a compound shown by formula (1) in the specification. The method comprises the following steps: (1) dropwise adding the compound shown by formula (2) in the specification into an organic solvent containing alkali carbonate and the compound shown by formula (3) in the specification so that the compound shown by formula (3) contacts and reacts with the compound shown by formula (2) to obtain the compound shown by formula (4); and (2) performing alkaline hydrolysis and acidification of the compound shown by formula (4) to obtain the compound shown by formula (1). By adopting the preparation method, the target compound can be prepared with relatively high yield in relatively mild reaction conditions.
