55120-56-4

Basic information

• Product Name: 5-amino-2-bromophenol
• Synonyms: 5-amino-2-bromophenol;2-BroMo-5-aMinophenol
• CAS NO: 55120-56-4
• Molecular Formula: C₆H₆BrNO
• Molecular Weight: 188.02
• Mol File: 55120-56-4.mol
• Article Data: 11

Chemical Properties

• Melting Point: 150 °C
• Boiling Point: 261.1±20.0 °C(Predicted)
• Appearance: /
• Density: 1.768±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 8.48±0.10(Predicted)
• CAS DataBase Reference: 5-amino-2-bromophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-2-bromophenol(55120-56-4)
• EPA Substance Registry System: 5-amino-2-bromophenol(55120-56-4)

Safety Data

• Hazardous Substances Data: 55120-56-4(Hazardous Substances Data)

Upstream product

• 591-27-5 m-Hydroxyaniline 
• 52427-05-1 2-bromo-5-nitrophenol 
• 121-88-0 5-Nitro-2-aminophenol 
• 860209-11-6 3-amino-2-bromo-5-nitro-phenol 
• 116296-08-3 acetic acid-(3-hydroxy-5-nitro-anilide) 
• 586-11-8 3,5-dinitrophenol 
• 618-64-4 3-Amino-5-nitro-phenol 
• 55065-94-6 N-(4-bromo-3-hydroxyphenyl)acetamide 
• 19056-40-7 4-bromo-3-methoxyaniline 

Downstream Products

• 6626-15-9 4-Bromoresorcinol 
• 127943-83-3 3-(benzyloxy)-4-bromoaniline 
• 1584736-37-7 C₂₄H₂₃NO₆ 
• 1584736-36-6 C₂₄H₂₃NO₆ 
• 1584736-34-4 C₁₇H₁₆BrNO₅ 
• 1584736-31-1 C₉H₁₀BrNO₃ 
• 1005786-70-8 N-[6-(5-amino-2-bromophenoxy)imidazo[1,2-b]pyridazin-2-yl]cyclopropanecarboxamide 
• 26093-31-2 7-amino-4-methylcoumarin. 

Relevant articles and documents

Coumarins by Direct Annulation: β-Borylacrylates as Ambiphilic C3-Synthons

Modular β-borylacrylates have been validated as programmable, ambiphilic C3-synthons in the cascade annulation of 2-halo-phenol derivatives to generate structurally and electronically diverse coumarins. Key to this [3+3] disconnection is the BPin unit which serves a dual purpose as both a traceless linker for C(sp2)–C(sp2) coupling, and as a chromophore extension to enable inversion of the alkene geometry via selective energy transfer catalysis. Mild isomerisation is a pre-condition to access 3-substituted coumarins and provides a handle for divergence. The method is showcased in the synthesis of representative natural products that contain this venerable chemotype. Facile entry into π-expanded estrone derivatives modified at the A-ring is disclosed to demonstrate the potential of the method in bioassay development or in drug repurposing.

Discovery of meta-amido bromophenols as new antitubercular agents

A series of meta-amido bromophenol derivatives were designed and synthesized. The compounds were found to potently inhibit the growth of Mycobacterium tuberculosis H37Ra. They also exhibited moderate inhibitory activity against Mycobacterium tuberculosis H37Rv and multidrug-resistant strains. The compounds did not show inhibitory activity against normal Gram-positive and Gram-negative bacteria. Moderate cytotoxicities and good metabolic stability were observed for the selected compounds. The results demonstrated meta-amido bromophenols as a new class of antitubercular agents with good potentials.

SUBSTITUTED PYRIDOBENZODIAZEPINONE-DERIVATIVES AND USE THEREOF

The present application relates to novel (3-hydroxyphenyl)amino-substituted pyrido[2,3-b][1,5]benzodiazepin-5-one derivatives, to processes for preparation thereof, to the use thereof alone or in combination for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially of angiogenic disorders and hyperproliferative disorders in which neovascularization plays a role, for example ophthalmological disorders and cancers and tumours. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.