55130-90-0Relevant academic research and scientific papers
Synthesis of 1,2-Dihydroisoquinoline-1-Carboxylates Under Cobalt Catalysis
Zagorska, Paula Amanda,Grigorjeva, Liene,Bolsakova, Jekaterina
, (2021)
[Figure not available: see fulltext.] A study of cobalt-catalyzed C–H functionalization of phenylglycine derivatives with alkynes is described. During the optimization studies, a range of cobalt catalysts, oxidants, base additives, and reaction solvents were evaluated. Product yield dependence on phenylglycine ester substituent was evaluated. Conditions for 1,2-dihydroisoquinoline synthesis with acceptable yield were found.
