55153-19-0

Upstream product

• 17264-78-7 sodium 2-methoxybenzoate 
• 70-11-1 α-bromoacetophenone 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 98-86-2 acetophenone 
• 16463-34-6 potassium 2-methoxybenzoate 
• 579-75-9 2-Methoxybenzoic acid 

Downstream Products

• 98-86-2 acetophenone 

Relevant academic research and scientific papers

Palladium-Catalyzed Chemo- and Enantioselective C?O Bond Cleavage of α-Acyloxy Ketones by Hydrogenolysis

A chemoselective C?O bond cleavage of the ester alkyl side-chain of α-acyloxy ketones was realized for the first time by a highly efficient palladium-catalyzed hydrogenolysis (S/C=6000, the highest catalytic efficiency by far). Furthermore, a kinetic resolution of α-acyloxy ketones was first developed by enantioselective hydrogenolysis with good yields and up to 99 % ee.

Palladium-catalyzed asymmetric hydrogenation of α-acyloxy-1- arylethanones

First hand: The first example of a palladium-catalyzed asymmetric hydrogenation of α-acyloxy ketones (1) was accomplished to give the hydrogenated products 2 with by far the highest catalytic efficiency in up to quantitative conversions and excellent enantioselectivities. The hydrogenated products could serve as important intermediates for the preparation of many drug candidates. TFE=2,2,2-trifluoroethanol. Copyright

One-pot synthesis of phenacyl esters from acetophenone, [Bmim]Br 3, and potassium salts of carboxylic acids under solvent-free conditions

One-pot synthesis of phenacyl esters from acetophenone, [Bmim]Br3, and potassium salts of carboxylic acids under solvent-free conditions gave the corresponding phenacyl esters with excellent yields. Copyright Taylor & Francis Group, LLC.

N-Disubstituted carbamoyloxy flavones

The invention relates to new flavone derivaties which have at least one N-disubstituted carbamoyloxy unit (OOCNR6(R7))coupled directly to one or both aromatic rings of the flavone molecule.

Separation of Polar and Steric Effects in Reactions of ortho-Substituted Benzoate Ions with para-Substituted Phenacyl Bromides

The second order rate constants for SN2 reactions of several ortho-substituted benzoate ions with several para-substituted phenacyl bromides have been measured in 90percent acetone - 10percent water (v/v) mixture at 35 deg C.Satisfactory correl

The Separation of Polar and Steric Effects in the Reaction of ortho-Substituted Benzoate Ions with Ethyl Bromoacetate

The second-order rate coefficients for the reactions of ortho-substituted benzoate ions with ethyl bromoacetate have been measured in a 90percent acetone-10percent water (v/v) mixture at three different temperatures and the results have been compared with those of phenacyl bromide.The order of reactivity of ortho-substituted benzoate ions with ethyl bromoacetate is almost the same as that observed for the reaction of ortho-substituted benzoate ions with phenacyl bromide.Attempts have been made to analyse the rate data in terms of electronic and steric effects by employing Charton's treatment.Analysis of the results shows that the localized effect is predominant over the delocalized effect in each reaction series and electron-releasing groups favour the reaction and electron-withdrawing groups retard it.The steric term is rate accelerating.The ΔS(excit.) values for all the ortho-substituted benzoate ions are negative and it appears that the bulk effect of the substituent plays a part in the variation of ΔS(excit.).

Influence of ortho-Substituents in Anionic Surfactant Catalyzed Reaction of Benzoate Ions with Phenacyl Bromide

The reaction of ortho-substituted benzoate ions and phenacyl bromide in the presence of anionic surfactant, sodium dodecyl sulphate (NaLS) has been studied in acetone-water (68:32, v/v) at 35 deg C.A plot of rate constants versus surfactant concentrations