55191-13-4Relevant academic research and scientific papers
A CONVENIENT SYNTHESIS OF PHOSPHOENOLPYRUVATE VIA SILYLESTER INTERMEDIATE
Sekine, Mitsuaki,Futatsugi, Tetsuaki,Yamada, Kohji,Hata, Tsujiaki
, p. 371 - 372 (1980)
Phosphoenolpyruvate was synthesized in high yield by a simple procedure starting from pyruvic acid and dimethyl trimethylsilyl phosphite through trimethylsililation, bromination, and the Perkow reaction.
Bioinspired Total Synthesis of (±)-Chaetophenol C Enabled by a Pd-Catalyzed Cascade Cyclization
Li, Yun,Zhang, Qingyu,Wang, Hongyu,Cheng, Bin,Zhai, Hongbin
supporting information, p. 4387 - 4390 (2017/08/23)
A novel Pd(II)-catalyzed cascade reaction has been developed that consists of a highly regio- and stereoselective oxa [4 + 2] cycloaddition reaction of o-alkynylbenzaldehydes and an intramolecular carboxylic group quenching of the in situ generated oxonium ion. This new reaction provides a one-step construction of the tetracyclic core structure of chaetophenol C from two simple starting materials. The developed chemistry was successfully applied to the first total synthesis of chaetophenol C and dozens of its analogues.
Silyl Phosphites. Part 20. A Facile Synthesis pf Phosphoenolpyruvate and Its Analogue Utilizing in siti Generated Trimethylsilyl Bromide
Sekine, Mitsuo,Futatsugi, Tetsuaki,Yamada, Kohji,Hata, Tsujiaki
, p. 2509 - 2514 (2007/10/02)
Phosphoenolpyruvate (PEP) has been synthesized from pyruvic acid and dimethyl trimethylsilyl phosphite in high yield by a new route which involves, successively, trimethylsilylation, bromination, and a Perkow reaction.A PEP analogue of 1-(dihydroxyphosphinyl)vinyl phosphate (1) has also been prepared.
