551943-83-0

Basic information

• Product Name: 1-Piperazineethanol, 4-[(4-methylphenyl)sulfonyl]-β-phenyl-, (βR)-
• Synonyms: 1-Piperazineethanol, 4-[(4-methylphenyl)sulfonyl]-β-phenyl-, (βR)-
• CAS NO: 551943-83-0
• Molecular Formula: C19H24N2O3S
• Molecular Weight: 360.477
• Mol File: 551943-83-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Piperazineethanol, 4-[(4-methylphenyl)sulfonyl]-β-phenyl-, (βR)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazineethanol, 4-[(4-methylphenyl)sulfonyl]-β-phenyl-, (βR)-(551943-83-0)
• EPA Substance Registry System: 1-Piperazineethanol, 4-[(4-methylphenyl)sulfonyl]-β-phenyl-, (βR)-(551943-83-0)

Safety Data

• Hazardous Substances Data: 551943-83-0(Hazardous Substances Data)

Usage

Molecular weight

401.52 g/mol

Chiral compound

A compound that has a molecule with a structure that is mirror-symmetrical to its original molecule, but the two forms cannot be superimposed on each other.

Building block in the synthesis of biologically active molecules

A simple molecule that is used as a starting material in the creation of more complex molecules, particularly in the development of potential drug candidates.

Suitable for use in medicinal chemistry and drug discovery

The properties and structure of the compound make it useful in the creation of new compounds with potential therapeutic applications.

Upstream product

• 56613-80-0 D-2-phenylglycinol 
• 20989-17-7 Phenylglycinol 
• 52601-81-7 4-Methyl-N,N-bis<2-(methylsulfonyloxy)ethyl>benzolsulfonamid 

Downstream Products

• 551943-86-3 3,5-Bis-trifluoromethyl-benzoic acid (R)-2-phenyl-2-[4-(toluene-4-sulfonyl)-piperazin-1-yl]-ethyl ester 
• 551943-88-5 1-{(R)-2-[1-(3,5-Bis-trifluoromethyl-phenyl)-vinyloxy]-1-phenyl-ethyl}-4-(toluene-4-sulfonyl)-piperazine 
• 346417-75-2 2-[2-(4-{(R)-2-[(S)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-1-phenyl-ethyl}-piperazin-1-yl)-ethoxy]-acetamide 
• 346417-74-1 2-[2-(4-{(R)-2-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-1-phenyl-ethyl}-piperazin-1-yl)-ethoxy]-acetamide 
• 346417-72-9 2-(4-{(R)-2-[(S)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-1-phenyl-ethyl}-piperazin-1-yl)-acetamide 
• 346417-71-8 2-(4-{(R)-2-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-1-phenyl-ethyl}-piperazin-1-yl)-acetamide 
• 551943-95-4 1-{(R)-2-[(S)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-1-phenyl-ethyl}-piperazine 
• 551943-93-2 1-{(R)-2-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-1-phenyl-ethyl}-piperazine 

Relevant articles and documents

Alpha-arylethylpiperazine derivatives as neurokinin antagonists

The invention relates to new α-arylethylpiperazine derivatives, which are useful as neurokinin receptor antagonists (NK1antagonists). It also relates to processes for the preparation of said α-arylethylpiperazine derivatives, to their use for the prevention and/or treatment of a condition associated with pathogical levels of substance P in a patient and to pharmaceutical compositions containing them.