551944-07-1Relevant academic research and scientific papers
Design, synthesis, and structure-activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis
Liu, Weiguo,Chen, Steve,Dropinski, James,Colwell, Lawrence,Robins, Michael,Szymonifka, Michael,Hayes, Nancy,Sharma, Neelam,MacNaul, Karen,Hernandez, Melba,Burton, Charlotte,Sparrow, Carl P.,Menke, John G.,Singh, Sheo B.
, p. 4574 - 4578 (2007/10/03)
A series of podocarpic acid amides were identified as potent agonists for Liver X receptor α and β subtypes, which are members of a nuclear hormone receptor superfamily that are involved in the regulation of a variety of metabolic pathways including chole
Therapeutic compounds for treating dyslipidemic conditions
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, (2008/06/13)
Compounds of Formula I and the pharmaceutically acceptable salts and esters thereof, wherein Z is selected from the group consisting of: (a) Formula Ia ?and (b) Formula Ib are novel LXR agonists and are useful in the treatment of dyslipidemic conditions p
