55198-73-7

Basic information

• Product Name: N-phenyl-N-methyl-p-(N',N'-dimethylamino)benzamide
• Synonyms: N-phenyl-N-methyl-p-(N',N'-dimethylamino)benzamide
• CAS NO: 55198-73-7
• Molecular Weight: 254.332
• Mol File: 55198-73-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-phenyl-N-methyl-p-(N',N'-dimethylamino)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-N-methyl-p-(N',N'-dimethylamino)benzamide(55198-73-7)
• EPA Substance Registry System: N-phenyl-N-methyl-p-(N',N'-dimethylamino)benzamide(55198-73-7)

Safety Data

• Hazardous Substances Data: 55198-73-7(Hazardous Substances Data)

Upstream product

• 619-84-1 p-N,N-dimethylaminobenzoic acid 
• 4755-50-4 4-(dimethylamino)benzoyl chloride 
• 100-61-8 N-methylaniline 
• 784-94-1 C₁₄H₁₄N₂O 
• 74-88-4 methyl iodide 

Downstream Products

• 1477586-03-0 N-phenyl-N-methyl-ap-(methylamino)benzamide 

Relevant articles and documents

Acetic Acid Accelerated Visible-Light Photoredox Catalyzed N-Demethylation of N,N-Dimethylaminophenyl Derivatives

N,N-Dimethylaminophenyl moiety is a common fragment in medicinal chemistry as several pharmaceuticals bearing this privileged motif are on the market and under clinical evaluation. Oxidative N-demethylation is generally regarded as the major metabolic pathway. However, pharmacokinetics, metabolites studies as well as the further structural modification are precluded by the impracticality of chemical synthesis. Here we report that acetic acid can significantly accelerate visible-light photoredox catalyzed N-demethylation of N,N-dimethylaminophenyl derivatives. This approach is easy for large scale reaction and even for potential industrial manufacture. (Figure presented.).