55214-31-8

Basic information

• Product Name: Piperazine, 1-(3-chloropropyl)-4-(4-methylphenyl)-
• CAS NO: 55214-31-8
• Molecular Formula: C14H21ClN2
• Molecular Weight: 252.787
• Mol File: 55214-31-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Piperazine, 1-(3-chloropropyl)-4-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-(3-chloropropyl)-4-(4-methylphenyl)-(55214-31-8)
• EPA Substance Registry System: Piperazine, 1-(3-chloropropyl)-4-(4-methylphenyl)-(55214-31-8)

Safety Data

• Hazardous Substances Data: 55214-31-8(Hazardous Substances Data)

Upstream product

• 39593-08-3 (4-methylphenyl)piperazine 
• 109-70-6 1.3-chlorobromopropane 

Downstream Products

• 91532-15-9 3-[3-(4-p-Tolyl-piperazin-1-yl)-propyl]-3H-benzo[d][1,2,3]triazin-4-one 
• 174519-54-1 N¹-[3-(4-p-Tolyl-piperazin-1-yl)-propyl]-ethane-1,2-diamine 
• 114694-61-0 1-[4-(2-chloro-phenyl)-piperazino]-3-(4-p-tolyl-piperazino)-propane 
• 116030-53-6 1-(4-o-tolyl-piperazino)-3-(4-p-tolyl-piperazino)-propane 
• 114694-62-1 1-[4-(4-chloro-phenyl)-piperazino]-3-(4-p-tolyl-piperazino)-propane 
• 114694-58-5 1-[4-(3-chloro-phenyl)-piperazino]-3-(4-p-tolyl-piperazino)-propane 
• 116030-52-5 1-(4-m-tolyl-piperazino)-3-(4-p-tolyl-piperazino)-propane 
• 119696-37-6 1-(4-phenyl-piperazino)-3-(4-p-tolyl-piperazino)-propane 

Relevant articles and documents

Design, synthesis, and biological evaluation of structurally constrained hybrid analogues containing ropinirole moiety as a novel class of potent and selective dopamine D3 receptor ligands

Two series of hybrid analogues were designed, synthesized, and evaluated as a novel class of selective ligands for the dopamine D3 receptor. Binding affinities of target compounds were determined (using the method of radioligand binding assay). Compared to comparator agent BP897, compounds 2a and 2c were found to demonstrate a considerable binding affinity and selectivity for D3 receptor, and especially compound 2h was similarly potent and more selective D3R ligand than BP897, a positive reference. Thus, they may provide valuable information for the discovery and development of highly potent dopamine D3 receptor ligands with outstanding selectivity.

Benzo- and thieno-triazine-1,2,3 ones-4

This invention relates to benzo- and thieno-triazine-1,2,3 ones-4 represented by the formula STR1 in which m is 2, 3 or 4, X is the vinylene group --CH=CH-- or a sulfur atom; R1 and R2 can be alike or different and are hydrogen, halogen, a lower alkyl radical, lower alkoxy radical or trifluoromethyl radical; when X is --CH--CH-- n is 0, 1 or 2 and R is hydrogen, halogen, a lower alkyl radical, lower alkoxy radical or nitro group; when X is a sulfur atom, R is hydrogen or constitutes a --CH2 --4 chain between the two open positions of the thiophenic ring. The compounds are useful as antidepressant drugs.