552291-48-2

Upstream product

• 530440-44-9 C₂₂H₂₂F₆N₂O₂ 
• 530441-99-7 2-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-1-phenyl-ethanone 
• 552291-47-1 C₂₂H₂₄F₆N₂O 
• 108-24-7 acetic anhydride 

Relevant academic research and scientific papers

And as the antagonist aminopyrrolidine deriv. NK1 aminopiperidine (by machine translation)

A NK 1 antagonist having the formula (I), wherein Ar 1 and Ar 2 are optionally substituted phenyl or heteroaryl, X 1 is an ether, thio or imino linkage, R 4 and R 5 are not both H or alkyl, and the remaining variables are as defined in the specification, useful for treating a number of disorders, including emesis, depression, anxiety and cough. Pharmaceutical compositions. Methods of treatment and combinations with other agents are also disclosed.