552331-05-2 Usage
Description
6-Bromo-1,3-dichloroisoquinoline is a heterocyclic organic compound characterized by a molecular formula of C9H4BrCl2N. It features the presence of both bromine and chlorine atoms within its structure, making it a versatile building block in the realm of organic chemistry. 6-Bromo-1,3-dichloroisoquinoline is known for its potential applications in the synthesis of pharmaceuticals and agrochemicals, as well as for its biological and pharmacological activities.
Uses
Used in Pharmaceutical Industry:
6-Bromo-1,3-dichloroisoquinoline serves as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with specific therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 6-Bromo-1,3-dichloroisoquinoline is utilized as a precursor for the production of agrochemicals. Its chemical properties enable the creation of compounds that can be used in pest control and crop protection, thereby enhancing agricultural productivity.
Used in Organic Chemistry Research:
6-Bromo-1,3-dichloroisoquinoline is also employed as a research compound in organic chemistry. Its reactivity and structural features make it an important tool for studying reaction mechanisms and exploring new synthetic pathways.
Synthesis:
6-Bromo-1,3-dichloroisoquinoline can be synthesized through various methods, one of which involves the reaction between 1,3-dichloroisoquinoline and a brominating agent. This synthesis process highlights the compound's potential for further modification and functionalization, expanding its applicability in different chemical domains.
Check Digit Verification of cas no
The CAS Registry Mumber 552331-05-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,2,3,3 and 1 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 552331-05:
(8*5)+(7*5)+(6*2)+(5*3)+(4*3)+(3*1)+(2*0)+(1*5)=122
122 % 10 = 2
So 552331-05-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H4BrCl2N/c10-6-1-2-7-5(3-6)4-8(11)13-9(7)12/h1-4H
552331-05-2Relevant articles and documents
Synthesis of medical intermediate disubstituted N-containing heterocycle amine compound
-
, (2019/01/06)
The invention relates to synthesis of a medical intermediate disubstituted N-containing heterocycle amine compound. The synthesis comprises the following steps: reacting 5-bromo-2-carboxy-phenylaceticacid, urea and o-dichlorobenzene as raw materials to obtain 6-bromoisoquinoline-1, 3 (2H,4H)-dione; allowing the 6-bromoisoquinoline-1, 3 (2H,4H)-dione to react with phenyl dichloro sphosphineoxide,adding tetrahydrofuran to precipitate out, adjusting the pH value, and then passing through a column to obtain 1, 3-dichloro-6-bromoisoquinoline; then adding glacial acetic acid, red phosphorus and hydroiodic acid, and after the reaction, determining whether the reaction is complete or not by TLC, subjecting the filtrate and the filter cake to repeated fine treatment to obtain 3-chloro-6-bromoisoquinoline; adding copper sulfate pentahydrate, 6-bromo-3-chloroisoquinoline and a large amount of 15% ammonia water to react in a high-pressure kettle, extracting and passing column for many times according to different requirements to obtain the final product 3-chloro-6-aminoisoquinoline.
Kinase inhibitors
-
, (2008/06/13)
Compounds having the formula are useful for inhibiting protein kinases. Also disclosed are compositions which inhibit protein kinases and methods of inhibiting protein kinases in a patient.