55234-03-2Relevant academic research and scientific papers
A New, General Cyclopentenone Synthesis
Ceccherelli, Paolo,Curini, Massimo,Marcotullio, Maria Carla,Rosati, Ornelio,Wenkert, Ernest
, p. 311 - 315 (2007/10/02)
A new synthesis of cyclopentenones, involving an Rh(II)-catalyzed, intramolecular carbon-hydrogen insertion of diazomethyl ketones derived from α,β-unsaturated acids, is described.
Inducibility of an Enone Reductase System in the Fungus Beauveria sulfurescens: Application in Enantioselective Organic Synthesis
Fauve, Annie,Renard, Michel F.,Veschambre, Henri
, p. 4893 - 4897 (2007/10/02)
Microbiological reduction of α,β-unsaturated carbonyl compounds is studied.Inducibility of the enone reductase system of Beauveria sulfurescens is reported.The best inducer is shown to be cyclohex-2-en-1-one.An appropriate procedure using induced resting mycelium is developed to reduce substituted cyclohexenones that are shown to be unable to induce the reducing enzyme.Optically pure trans-(2R,6R)-(-)-2,6-dimethylcyclohexan-1-one and trans-(2R,6R)-(-)-2,6-dimethylcyclohexan-1-ol are obtained from (+/-)-2,6-dimethylcyclohex-2-en-1-one along with optically pure (6S)-(-)-2,6-dimethylcyclohex-2-en-1-one.
Oxidation of Enol Silyl Ethers: Preparation of Aeginetolide, Dihydroactinidiolide, and Actinidiolide
Rubottom, George M.,Juve, Henrik D.
, p. 422 - 425 (2007/10/02)
The preparation of the C11-terpenic lactones aeginetolide (1), dihydroactinidiolide (2), and actinidiolide (3) by using 1,3,3-trimethyl-2-(trimethylsiloxy)cyclohexene (9) as a common precursor is discussed.The key steps in the synthetic route involve the sequential m-chloroperbenzoic acid (MCPBA) oxidation and acetylation of 9 and of the siloxy diene 13 derived from 9.
