2570-68-5Relevant articles and documents
A NOVEL SYNTHESIS OF (E)-3,7-DIMETHYL-2-OCTENE-1,8-DIOL SECRETED BY THE AFRICAN MONARCH USING THE RING-OPENING REACTION OF α-METHYL-β-PROPIOLACTONE
Fujisawa, Tamotsu,Sato, Toshio,Kawara, Tatsuo,Noda, Atsunari
, p. 3193 - 3194 (1982)
The regioselective ring-opening reaction of α-methyl-β-propiolactone with 3,3-ethylenedioxybutylmagnesium bromide in the presence of copper(I) catalyst afforded 2-methyl-6-oxoheptanoic acid, which was easily converted into (E)-3,7-dimethyl-2-octene-1,8-diol in good yield.
Oxidative cleavage of cycloalkanones with dioxygen catalyzed by supported catalysts or homogeneous systems: Evidence for novel active ruthenium (II) and/or (III) species
Vennat, Maxence,Brégeault, Jean-Marie
, p. 9 - 15 (2010)
α-Substituted cycloalkanones are oxidized to oxo-acids by low-nuclearity complexes (Cu2+ or [VO2] +/[VO]2+ - exchanged Nafion beads), or homogeneous systems with ruthenium acetate complexes and [Ru(H 2O)6] (tosylate)2 in dioxygen (0.1 MPa) at 55-60 °C. The catalytic procedures compare well with previously described systems involving homogeneous catalysis with copper (II) or polyoxometalates such as "H8[PMo7V5O40] ·aq". The results complement the widely used oxidative methods for ketone cleavage in cases when protons and transition metal salts are involved. A tentative dioxygenase mechanism, involving peroxygen species, is proposed for these reactions.
Visible Light-Driven, Copper-Catalyzed Aerobic Oxidative Cleavage of Cycloalkanones
Xin, Hong,Duan, Xin-Hua,Yang, Mingyu,Zhang, Yiwen,Guo, Li-Na
, p. 8263 - 8273 (2021/06/30)
A visible light-driven, copper-catalyzed aerobic oxidative cleavage of cycloalkanones has been presented. A variety of cycloalkanones with varying ring sizes and various α-substituents reacted well to give the distal keto acids or dicarboxylic acids with moderate to good yields.
Sesterterpenoids from the sponge Sarcotragus sp.
Wang, Nan,Song, Jueun,Kyoung, Hwa Jang,Lee, Hyi-Seung,Li, Xian,Oh, Ki-Bong,Shin, Jongheon
, p. 551 - 557 (2008/12/23)
Nineteen new sesterterpenoids and eight known compounds were isolated from the sponge Sarcotragus sp. collected from Soheuksan Island, Korea. The structures of these compounds were determined to be linear sesterterpenoids containing furan or related oxygenated functionalities on the basis of combined chemical and spectroscopic analyses. In addition, the configurations of several previously undetermined compounds were assigned. Several compounds exhibited moderate to major antibacterial activity (compounds 1-3, 17, 18) and cytotoxicity (3, 11, 12) against the K562 cell line and inhibitory activity against isocitrate lyase (6, 13).