5524-30-1 Usage
Uses
Used in Pharmaceutical Research:
(2Z)-2-(6-methyl-1H-benzimidazol-2-yl)-3-(3-nitro-4-piperidin-1-ylphenyl)prop-2-enenitrile is used as a research compound for exploring its potential bioactivity and therapeutic applications. Its unique structure, which includes a benzimidazole ring and a nitrophenyl group, may contribute to its interaction with biological targets, making it a candidate for further investigation in drug discovery processes.
Used in Drug Development:
In the field of drug development, (2Z)-2-(6-methyl-1H-benzimidazol-2-yl)-3-(3-nitro-4-piperidin-1-ylphenyl)prop-2-enenitrile serves as a lead compound. Its chemical properties and potential reactivity allow it to be modified and optimized for specific pharmaceutical applications. Researchers can use (2Z)-2-(6-methyl-1H-benzimidazol-2-yl)-3-(3-nitro-4-piperidin-1-ylphenyl)prop-2-enenitrile as a starting point to design new drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 5524-30-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,2 and 4 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5524-30:
(6*5)+(5*5)+(4*2)+(3*4)+(2*3)+(1*0)=81
81 % 10 = 1
So 5524-30-1 is a valid CAS Registry Number.
5524-30-1Relevant academic research and scientific papers
Synthesis and evaluation of carbamate prodrugs of a phenolic compound
Igarashi, Yasushi,Yanagisawa, Erika,Ohshima, Toshihiro,Takeda, Shuichi,Aburada, Masaki,Miyamoto, Ken-Ichi
, p. 328 - 333 (2007/10/03)
A series of carbamates of the phenolic compound 1 were prepared and evaluated in vivo as its prodrug. Each carbamate was orally administered to rats, and plasma concentrations of the parent compound 1 were measured with the passage of time. We judged which carbamate was suitable for the prodrug of 1 from both the AUC value of 1 and absence of the carbamate in plasma. The AUC value of 1 after oral administration of 2b was approximately 40-fold higher than that for an administration of 1, and the bioconversion from 2b to 1 was excellent. As a whole, di-substituted carbamates resulted in higher plasma concentrations of 1 than did mono-substituted ones. However di-substituted carbamates were almost always detected in plasma. As a result, we found that the ethycarbamoyl derivative 2b demonstrates the best prodrug property in this series.
