5526-08-9

Basic information

• Product Name: 1,3-bis(2-aminophenyl)thiourea
• Synonyms: 1,3-bis(2-aminophenyl)thiourea
• CAS NO: 5526-08-9
• Molecular Weight: 258.347
• Mol File: 5526-08-9.mol

Chemical Properties

• CAS DataBase Reference: 1,3-bis(2-aminophenyl)thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis(2-aminophenyl)thiourea(5526-08-9)
• EPA Substance Registry System: 1,3-bis(2-aminophenyl)thiourea(5526-08-9)

Safety Data

• Hazardous Substances Data: 5526-08-9(Hazardous Substances Data)

Upstream product

• 2719-30-4 o-nitrophenylisothiocyanate 
• 95-54-5 1,2-diamino-benzene 
• 75-15-0 carbon disulfide 

Relevant articles and documents

Anion binding of tris-(thio)urea ligands

Two tridentate tris-(thio)urea ligands (L2 and L3) have been synthesized. Ligand L2 forms a 2:2 complex (1) with the (H2PO4·HPO4)3- dimer. 1H NMR and UV-vis titrations revealed that the mixed urea-thiourea ligand, L2, shows considerable anion binding affinities, while the tris-thiourea ligand, L3, undergoes deprotonation in the presence of basic anions.

A simple and straightforward synthesis of phenyl isothiocyanates, symmetrical and unsymmetrical thioureas under ball milling

Promoted by KOH under ball milling, anilines were efficiently transformed into isothiocyanates (in presence of 5.0 equiv. CS2) or symmetrical thioureas (in presence of 1.0 equiv. CS2), without using any other harsh or toxic decomposition reagent. Some in situ generated isothiocyanates can directly "click" with other amines to afford unsymmetrical thioureas.