552832-91-4Relevant academic research and scientific papers
Nonbenzamidine tetrazole derivatives as factor Xa inhibitors
Quan, Mimi L.,Ellis, Christopher D.,He, Ming Y.,Liauw, Ann Y.,Woerner, Francis J.,Alexander, Richard S.,Knabb, Robert M.,Lam, Patrick Y. S.,Luettgen, Joseph M.,Wong, Pancras C.,Wright, Matthew R.,Wexler, Ruth R.
, p. 369 - 373 (2003)
Factor Xa (fXa) is an important serine protease that holds the central position linking the intrinsic and extrinsic activation mechanisms in the blood coagulation cascade. Therefore, inhibition of fXa has potential therapeutic applications in the treatmen
