552841-06-2Relevant academic research and scientific papers
A green and highly efficient synthesis of 5,5-(phenylmethylene)bis(1,3-dioxane-4,6-dione) derivatives in biobased gluconic acid aqueous solution
Xu, Zhaohui,Zhou, Peng,Tu, Yuanhong,Liu, Deyong,Liao, Weilin,Liao, Chuanwen
, p. 1115 - 1122 (2017/06/13)
A green and highly efficient synthesis of 5,5-(phenylmethylene)bis(1,3-dioxane-4,6-dione) derivatives through tandem Knoevenagel condensation and Michael addition of aromatic aldehydes and 1,3-dioxane-4,6-dione in gluconic acid aqueous solution (GAAS) is
Synthesis of tetraketones in water and under catalyst-free conditions
Yu, Jian-Jun,Wang, Li-Min,Liu, Jin-Qian,Guo, Feng-Lou,Liu, Ying,Jiao, Ning
scheme or table, p. 216 - 219 (2011/03/19)
A simple, environmentally friendly, tandem Knoevenagel condensation and Michael addition procedure is reported. The reactions between cyclic-13-diketones and a variety of aldehydes were carried out in water to afford tetraketones (64-99%). In this green synthetic protocol, the solvent water itself catalysed the reaction by hydrogen bonding, thus avoiding the use of any other catalysts to make the work up procedure easier.
