552848-65-4Relevant academic research and scientific papers
Preparation of potential inhibitors of the mur-pathway enzymes on solid support using an acetal linker
Maletic, Milana,Antonic, Jelena,Leeman, Aaron,Santorelli, Gina,Waddell, Sherman
, p. 1125 - 1128 (2007/10/03)
Here, we report a novel strategy for the combinatorial or parallel solid-phase synthesis of potential inhibitors of the mur-pathway enzymes. The strategy involves the efficient use of p-alkoxybenzylidene acetal linker for reversible immobilization of sugar scaffolds to solid phase. This methodology was used to synthesize several glycopeptides on solid phase in good yields.
