552883-91-7Relevant academic research and scientific papers
SUBSTITUTED 1, 6-NAPHTHYRIDINE INHIBITORS OF CDK5
-
Page/Page column 55; 64-65, (2021/04/10)
Disclosed are compounds having structural formula I, and related salts and pharmaceutical compositions. Also disclosed are therapeutic methods, e.g., of treating diseases and conditions such as kidney disease, kidney failure, kidney stones, or polycystic kidney disease, using the compounds of formula (I), and related salts and pharmaceutical compositions.
HETEROCYCLIC COMPOUND
-
Paragraph 0564; 0647; 0648, (2017/04/11)
The present invention provides a heterocyclic compound having a CDK8 and/or CDK19 inhibitory effect. The present invention provides a compound represented by formula (I) (in the formula, the symbols are as defined in the description) or a salt thereof.
Heterocyclic compound
-
Paragraph 0173, (2017/09/28)
本發明提供一種具有CDK8/19抑制活性之雜環化合物。本發明提供一種如下式代表之化合物(其中各代號均如本文之定義)或其鹽。 The present invention provides a heterocyclic compound possessing CDK8/19 inhibitory activity. The present invention provides a compound represented by the formula wherein each symbol is as defined herein, or a salt thereof.
The design and development of 2-aryl-2-hydroxy ethylamine substituted 1H,7H-pyrido[1,2,3-de]quinoxaline-6-carboxamides as inhibitors of human cytomegalovirus polymerase
Tanis, Steven P.,Strohbach, Joseph W.,Parker, Timothy T.,Moon, Malcom W.,Thaisrivongs, Suvit,Perrault, William R.,Hopkins, Todd A.,Knechtel, Mary L.,Oien, Nancee L.,Wieber, Janet L.,Stephanski, Kevin J.,Wathen, Michael W.
scheme or table, p. 1994 - 2000 (2010/10/02)
Discovery efforts were focused on identifying a non-nucleoside antiviral for treating infections caused by human cytomegalovirus (HCMV) with equal or better potency and diminished toxicity compared to current therapeutics. This Letter describes the HCMV D
PYRIDOQUINOXALINE ANTIVIRALS
-
, (2008/06/13)
The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof wherein R1 and R2 are as defined in the specification. The compounds are useful for the treatment of viral infections.
