552888-46-7

Upstream product

• 211621-55-5 3,4,6-tri-O-benzyl-2-nitro-D-galactal 
• 552888-37-6 N-(tert-butoxycarbonyl)-O-(3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranosyl)-L-threonine methyl ester 
• 60538-19-4 N-(tert-butoxycarbonyl)-l-threonine methyl ester 
• 67-56-1 methanol 
• 552888-44-5 O-(2-amino-3,4,6-tri-O-benzyl-2-deoxy-α-D-galactopyranosyl)-N-(tert-butoxycarbonyl)-L-threonine methyl ester 
• 503-38-8 trichloromethyl chloroformate 

Downstream Products

• 552888-45-6 N-(methoxycarbonylamino)-O-(3,4,6-tri-O-benzyl-2-deoxy-2-methoxycarbonylamino-2-nitro-α-D-galactopyranosyl)-L-threonine methyl ester 

Relevant academic research and scientific papers

O-glycosyl amino acids by 2-nitrogalactal concatenation - Synthesis of a Mucin-type O-glycan

Base-promoted Michael-type addition of N-Boc- and N-Fmoc-protected serine and threonine esters to 2-nitrogalactal derivatives 2 and 26 led highly selectively to α-glycosides 4a-d and 27a,c, respectively. Ensuing transformation of threonine derivative 4d a