552890-50-3

Upstream product

• 552890-57-0 2,2-Dimethyl-propionic acid (2R,3S,5R,6R)-6-acetoxy-5-benzyloxy-2-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-pyran-3-yl ester 
• 552890-58-1 2,2-Dimethyl-propionic acid (2R,3S,5R,6S)-5-benzyloxy-2-(2,2-dimethyl-propionyloxymethyl)-6-hydroxy-tetrahydro-pyran-3-yl ester 
• 100-44-7 benzyl chloride 
• 1212-08-4 S-Phenyl benzenethiosulfonate 
• 617673-33-3 2,2-Dimethyl-propionic acid (2R,3S,5R)-6-acetoxy-5-benzyloxy-2-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-pyran-3-yl ester 
• 553662-54-7 (2R,3S,5R,6S)-6-Allyl-2-[(5S,6S,9S)-1-benzenesulfonylmethyl-9-benzyloxy-7-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-10-(4-methoxy-benzyloxy)-5,6-dimethyl-dec-2-ynyl]-5-benzyloxy-tetrahydro-pyran-3-ol 
• 553662-57-0 Acetic acid (2S,3S)-7-((2R,3S,5R,6S)-6-allyl-5-benzyloxy-3-hydroxy-tetrahydro-pyran-2-yl)-8-benzenesulfonyl-1-[(S)-2-benzyloxy-3-(4-methoxy-benzyloxy)-propyl]-4-methoxy-2,3-dimethyl-oct-5-ynyl ester 
• 552890-48-9 Acetic acid (2S,3S)-3-((2S,3R,4aS,6S,9S,9aR)-2-allyl-9-benzenesulfonylmethyl-3-benzyloxy-3,4,4a,6,9,9a-hexahydro-2H-1,5-dioxa-benzocyclohepten-6-yl)-1-((S)-2-benzyloxy-3-hydroxy-propyl)-2-methyl-butyl ester 
• 617673-38-8 (2S,5S,6S)-6-((2S,3R,4aS,6S,9S,9aR)-2-Allyl-9-benzenesulfonylmethyl-3-benzyloxy-3,4,4a,6,9,9a-hexahydro-2H-1,5-dioxa-benzocyclohepten-6-yl)-2-benzyloxy-5-methyl-heptane-1,4-diol 
• 552890-45-6 (2R,3S,4S,5S)-1-Benzyloxy-5-{2-[(S)-2-benzyloxy-3-(4-methoxy-benzyloxy)-propyl]-[1,3]dithian-2-yl}-4-methyl-hexane-2,3-diol 
• 617673-31-1 ((4S,5S)-5-{2-[(S)-2-Benzyloxy-3-(4-methoxy-benzyloxy)-propyl]-[1,3]dithian-2-yl}-3-methoxy-4-methyl-hex-1-ynyl)-trimethyl-silane 
• 617673-36-6 Acetic acid (2R,3S,5R,6S)-6-allyl-5-benzyloxy-2-((Z)-2-phenylsulfanyl-2-triethylsilanyl-vinyl)-tetrahydro-pyran-3-yl ester 

Downstream Products

• 552890-51-4 (2S,5S,6S)-6-[(2S,3R,4aS,6S,9S,9aR)-9-Benzenesulfonylmethyl-3-benzyloxy-2-(2-oxo-propyl)-3,4,4a,6,9,9a-hexahydro-2H-1,5-dioxa-benzocyclohepten-6-yl]-2-benzyloxy-1-(tert-butyl-dimethyl-silanyloxy)-5-methyl-heptan-4-one 
• 552890-55-8 C₃₅H₄₆O₈ 
• 552890-54-7 C₄₁H₅₀O₁₀S 

Relevant academic research and scientific papers

Synthesis of the JKLM-ring fragment of ciguatoxin

A stereoselective synthesis of the LM-ring fragment has been achieved starting from a sugar derivative. A stereoselective synthesis of the JKLM-ring fragment has been achieved through a coupling between two segments via heteroconjugate addition, seven-membered ether ring formation mediated by an acetylene cobalt complex, and spiroketalization reaction.

Synthesis of JKLM ring fragment of ciguatoxin via acetylene-cobalt strategy

A stereoselective synthesis of the JKLM ring fragment has been achieved through a coupling between two segments via heteroconjugate addition, seven-membered ether ring formation mediated by an acetylene cobalt complex and spiroketalization reaction.