55308-64-0

Usage

Molecular Structure

The compound consists of a s-triazolo isoquinoline ring system and an ethoxyphenyl group.

Usage

Commonly used in medicinal chemistry for the development of potential drug candidates.

Properties

Unique structural and pharmacological properties.

Potential

Has shown potential in pharmaceutical research for modulating specific biological targets or pathways.

Application

Useful for studying the mechanisms of various diseases and the development of new therapeutic agents.

Importance

Distinct chemical structure and potential pharmacological activity make it an important target for further research and development in the field of drug discovery.

Upstream product

• 75-03-6 ethyl iodide 
• 55309-05-2 2-(3-hydroxyphenyl)-5,6-dihydro-s-triazolo<5,1-a>isoquinoline 

Downstream Products

• 80830-10-0 2-(3,4-dihydroxyphenyl)-5,6-dihydro-s-triazolo<5,1-a>isoquinoline 
• 80830-11-1 2-(3-hydroxyphenyl)-5,6-dihydro-6β-hydroxy-s-triazolo<5,1-a>isoquinoline 
• 55309-05-2 2-(3-hydroxyphenyl)-5,6-dihydro-s-triazolo<5,1-a>isoquinoline 

Relevant academic research and scientific papers

2-Substituted phenyl-s-triazolo[5,1-a] isoquinoline compounds

A new process for preparing s-triazolo[5,1-a]-isoquinoline derivatives of the formula STR1 wherein A represents the group --CH2 --CH2 -- or --CH=CH--; R is selected from hydrogen, amino, lower alkylamino, di-lower alkylamino, acylamino, diacylamino, ureido, thioureido, carbethoxythioureido, benzoylthioureido, sulfhydryl, lower alkyl, trifluoromethyl, phenyl, substituted phenyl, pyridyl, methylpyridyl and dimethylpyridyl; and R1 and R2 each independently represents hydrogen or lower alkoxy, by condensation of a 2-amino-3,4-dihydro-1(2H)-isoquinolinone with an imidolyl, cyanamide, cyanic or thiocyanic derivative. New compounds of the formula I wherein A represents the group --CH2 --CH2 -- or --CH=CH--, R has the same meaning as above with the exclusion of hydrogen, methyl, phenyl, and trifluoromethyl, R1 and R2 have the same meaning as above, with the proviso that when A represents the group --CH=CH--, R cannot be tolyl or pyridyl. The new compounds and some of the intermediates of the process are active as antiinflammatories, CNS depressants and anti-fertility agents.

2-Substituted phenyl-5-triazols [5,1-a] isoquinoline compounds

A new process for preparing s-triazolo[5,1-a]-isoquinoline derivatives of the formula STR1 wherein A represents the group --CH2 --CH2 -- or --CH=CH--; R is selected from hydrogen, amino, lower alkylamino, di-lower alkylamino, acylamino, diacylamino, ureido, thioureido, carbethoxythioureido, benzoylthioureido, sulfhydryl, lower alkyl, trifluoromethyl, phenyl, substituted phenyl, pyridyl, methylpyridyl and dimethylpyridyl; and R1 and R2 each independently represents hydrogen or lower alkoxy; by condensation of a 2-amino-3,4-dihydro-1(2H)-isoquinolinone with an imidolyl, cyanamide, cyanic or thiocyanic derivative. New compounds of the formula I wherein A represents the group --CH2 --CH2 -- or --CH=CH--, R has the same meaning as above with the exclusion of hydrogen, methyl, phenyl, and trifluoromethyl, R1 and R2 have the same meaning as above, with the proviso that when A represents the group --CH=CH--, R cannot be tolyl or pyridyl. The new compounds and some of the intermediates of the process are active as antiinflammatories, CNS depressants and anti-fertility agents.