55312-97-5

Basic information

• Product Name: 2,5-Dimethylphenylacetyl chloride
• Synonyms: 2,5-Dimethylphenylacetyl chloride;Benzeneacetyl chloride, 2,5-dimethyl-
• CAS NO: 55312-97-5
• Molecular Formula: C₁₀H₁₁ClO
• Molecular Weight: 182.65
• Mol File: 55312-97-5.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 260.272 °C at 760 mmHg
• Flash Point: 113.995 °C
• Appearance: /
• Density: 1.118 g/cm³
• Vapor Pressure: 0.012mmHg at 25°C
• Refractive Index: 1.5290 to 1.5330
• CAS DataBase Reference: 2,5-Dimethylphenylacetyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dimethylphenylacetyl chloride(55312-97-5)
• EPA Substance Registry System: 2,5-Dimethylphenylacetyl chloride(55312-97-5)

Safety Data

• RIDADR: UN 3265 8/PG II
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 55312-97-5(Hazardous Substances Data)

Usage

General Description

2,5-Dimethylphenylacetyl chloride is a chemical compound with the formula C10H11ClO. It is a derivative of phenylacetyl chloride, with two methyl groups attached to the aromatic ring. 2,5-Dimethylphenylacetyl chloride is commonly used in organic synthesis as a reagent for introducing the acetyl group into various organic molecules. Its unique structure and reactive nature make it useful in the production of pharmaceuticals, agrochemicals, and other fine chemicals. It is important to handle 2,5-dimethylphenylacetyl chloride with care due to its corrosive and irritating properties, and it should only be used in well-ventilated areas and with proper personal protective equipment.

InChI:InChI=1/C10H11ClO/c1-7-3-4-8(2)9(5-7)6-10(11)12/h3-5H,6H2,1-2H3

Upstream product

• 106-42-3 para-xylene 
• 553-94-6 4-bromo-m-xylene 
• 79-04-9 chloroacetyl chloride 
• 1122-42-5 2-iodo-p-xylene 
• 95-72-7 2-chloro-1,4-dimethyl-benzene 
• 22118-09-8 2-bromoacetyl chloride 
• 824-45-3 2,5-dimethylbenzyl chloride 
• 16213-85-7 (2,5-dimethylphenyl)acetonitrile 
• 13612-34-5 2-(2,5-dimethylphenyl)acetic acid 

Downstream Products

• 55312-94-2 (2,5-Dimethyl-phenyl)-acetic acid 8-[2-(2,5-dimethyl-phenyl)-acetoxy]-octyl ester 
• 1228462-85-8 N-(4-cyano-1-methoxy-piperidin-4-yl)-2-(2,5-dimethyl-phenyl)-N-hydroxy-acetamide 
• 1228462-74-5 4-{[2-(2,5-dimethyl-phenyl)-acetyl]-hydroxy-amino}-1-methoxy-piperidine-4-carboxylic acid methyl ester 
• 1430587-57-7 C₂₇H₃₂N₆O₂ 
• 203313-47-7 methyl cis-1-[2-(2,5-dimethylphenyl)acetamido]-4-methoxycyclohexane-1-carboxylate 
• 58358-37-5 2,5-dimethylphenylacetic acid ethyl ester 
• 922516-14-1 N-[[1-[(2,5-dimethylphenyl)acetyl]-4-piperidinyl]carbonyl]-DL-serine methyl ester 
• 922516-15-2 methyl 2-[1-[(2,5-dimethylphenyl)acetyl]-4-piperidinyl]-4,5-dihydro-4-oxazolecarboxylate 
• 922516-16-3 methyl 2-[1-[(2,5-dimethylphenyl)acetyl]-4-piperidinyl]-4-oxazolecarboxylate 
• 922516-17-4 2-[1-[(2,5-dimethylphenyl)acetyl]-4-piperidinyl]-4-oxazole-carboxylic acid 
• 922516-13-0 1-[(2,5-dimethylphenyl)acetyl]-4-piperidinecarboxylic acid 

Relevant articles and documents

Method for preparing 2, 5-dimethylphenylacetyl chloride

The invention discloses a method for preparing 2, 5-dimethylphenylacetyl chloride, and belongs to the field of pesticide intermediate synthesis. According to the method, p-xylene is used as an initialraw material, chloromethylation, cyaniding, hydrolysis and acylating chlorination are carried out, 2, 5-dimethylphenylacetyl chloride is obtained after continuous reaction without purification, the total yield of the four steps of reaction is 75%, and the product purity is greater than 99.0%. The method is simple in process and only needs to purify the final product and is low in operation cost,mild in reaction condition and high in yield and product purity and is very easy to realize industrial production.

Synthesis method and application of 1, 3-bis(2, 5-dimethylphenyl)propan-2-one

The invention discloses a synthesis method of 1, 3-bis(2, 5-dimethylphenyl)propan-2-one. The method includes: taking 2, 5-dimethylphenylacetic acid as the raw material, carrying out acylation and ethyl esterification reaction to obtain the intermediate et

Preparation method and application of novel spiro compound

The invention discloses a preparation method and application of a novel spiro compound and belongs to the technical field of pesticide synthesis. Compared with the prior art, the preparation method and application have the advantage that the novel spiro c