55314-30-2Relevant academic research and scientific papers
DERIVATIVES OF 4-(N-AZACYCLOALKYL) ANILIDES AS POTASSIUM CHANNEL MODULATORS
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Page/Page column 19-20, (2009/01/24)
This invention provides potassium channel modulators which are compounds of formula I where at least one of W and Z is N; where the moiety is one of Groups A or B below A where Ar is a 1,2-fused, six membered ring aromatic group, bearing substituents R1 and R2 as defined below, and containing zero or one ring nitrogen atom; and where other substituents are defined herein. The invention also provides a composition comprising a pharmaceutically acceptable carrier and at least one of the following: i) a pharmaceutically effective amount of a compound of formula I and ii) a pharmaceutically acceptable salt, ester, or prodrug thereof. The invention also provides a method of preventing or treating a disease or disorder which is affected by activities of potassium channels, comprising administering to a patient in need thereof a therapeutically effective amount of a compound of formula I or a salt, ester, or prodrug thereof.
Herbicidal 1-pyridyltetrazolinones
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, (2008/06/13)
Herbicidal tetrazolinone derivatives of the formula: STR1 in which R1 is alkyl, haloalkyl, cycloalkyl, alkenyl, haloalkenyl, alkynyl or phenyl, and R2 is alkyl, haloalkyl, cycloalkyl, alkenyl, haloalkenyl, alkynyl or phenyl, or R1 and R2 together with the nitrogen atom to which they are bonded form an optionally benzofused heterocyclic ring, which is optionally substituted by C1-4 alkyl, n is 0, 1, 2 or 3, and R3 each independently is nitro, halogen, alkyl, haloalkyl, alkylthio or phenoxy.
A Model Study of the Role of the CONH2-group in the Redox Co-enzyme NAD(P)+-NAD(P)H. Chirality in 2,4-dimethyl-3-carbamoylpyridinium Cations
Hooff,H. J. G. van,Lier, P. M. van,Bastiaansen, L. A. M.,Buck, H. M.
, p. 191 - 192 (2007/10/02)
Experimental verification of chirality in 2,4-dimethyl-3-carbamoylpyridinium cations.
