55340-18-6

Upstream product

• 38861-88-0 4-isobutylbenzoic acid 
• 38861-78-8 1-(4-isobutyl-phenyl)-ethanone 
• 79-37-8 oxalyl dichloride 
• 538-93-2 1-phenyl-2-methylpropane 

Downstream Products

• 104252-84-8 2-(4-Isobutyl-benzoylamino)-pentanedioic acid 
• 110319-76-1 N-hydroxy-N-methyl-4-(2-methylpropyl)benzamide 
• 185101-76-2 1-(4-Isobutyl-phenyl)-2,2,2-tris-methylsulfanyl-ethanone 
• 154320-56-6 methyl 4-iso-butylbenzoate 
• 1014700-29-8 C₂₂H₂₆N₂O₂ 
• 1149727-77-4 tert-butyl [(1R)-1-{4-[5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl]phenyl}ethyl]carbamate 
• 1207192-75-3 C₁₉H₂₁F₃N₂O₃S 

Relevant academic research and scientific papers

Modular Tuning of Electrophilic Reactivity of Iridium Nitrenoids for the Intermolecular Selective α-Amidation of β-Keto Esters

We report herein an Ir-catalyzed intermolecular amino group transfer to β-keto esters (amides) to access α-aminocarbonyl products with excellent chemoselectivity. The key strategy was to engineer electrophilicity of the putative Ir-nitrenoids by tuning electronic property of the κ2-N,O chelating ligands, thus facilitating nucleophilic addition of enol π-bonds of 1,3-dicarbonyl substrates.

Liquid crystallinity of 2-fluorenyl 4-alkylbenzoates

The liquid crystallinity values of 2-fluorenyl 4-alkyl (pentadecyl, n-, or s-butyl)-benzoates were compared with those of biphenyl homologues. Cyano group or hydrogen was used as the end group at the 7-position of 2-fluorenol moiety. Methoxy and hydroxy groups in addition to hydrogen were examined as a lateral substituent at the 2-position of 4-alkylbenzoic acid unit. 7-Cyano-2-fluorenyl 2-hydroxy-4-pentadecylbenzoate shows very similar properties to those of 4′-cyanobiphenyl-4-yl 2-hydroxy-4-pentadecylbenzoate.

Acylamino-substituted hetrazepines

A hetrazepine of the formula given below and a pharmaceutical composition comprising a therapeutically effective amount of the hetrazepine and a pharmaceutically acceptable inert carrier are disclosed and are useful in treating disease in a warm-blooded animal induced by endogenously formed PAF; STR1 wherein the substituents are defined herein.

In Vivo Characterization of Hydroxamic Acid Inhibitors of 5-Lipoxygenase

The hydroxamic acid functionality can be incorporated into simple molecules to produce potent inhibitors of 5-lipoxygenase.The ability of many of these hydroxamates to inhibit leukotriene synthesis in vivo has been measured directly with a rat peritoneal anaphylaxis model.Despite their potent enzyme inhibitory activity in vitro, many orally dosed hydroxamic acids only weakly inhibited leukotriene synthesis in vivo.This discrepancy is attributable at least in part to the rapid metabolism of hydroxamates to the corresponding carboxylic acids, which are inactive against the enzyme.A study of the structural features that affect this metabolism revealed that 2-arylpropionohydroxamic acids are relatively resistant to metabolic hydrolysis.Several members of this class of hydroxamates are described that are orally active inhibitors of leukotriene synthesis.