553630-41-4Relevant academic research and scientific papers
Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2
Grimstrup, Marie,Rist, ystein,Receveur, Jean-Marie,Frimurer, Thomas M.,Ulven, Trond,Mathiesen, Jesper M.,Kostenis, Evi,Hoegberg, Thomas
scheme or table, p. 1181 - 1185 (2010/06/15)
Structure-activity relationships have been established by exploring the eastern and western side of 5-thiazolyleacetic acids as CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells) antagonists. Benzhydryl motifs in the 2-position of
THIAZOLE DERIVATIVES, THEIR PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY
-
Page/Page column 39, (2008/06/13)
The invention provides compounds of formula (I), or a pharmaceutically acceptable salt thereof, wherein A, R1, R2 and R3 are as defined in the specification; a process for their preparation; pharmaceutical compositions con
