553645-76-4

Upstream product

• 297143-31-8 (1S,3R,4R)-2-azabicyclo[2.2.1]heptane-3-carboxylic acid methyl ester 
• 204327-16-2 (1S,3R,4R)-2-azabicyclo[2.2.1]heptane-3-(R)-methylmethanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 98-59-9 p-toluenesulfonyl chloride 
• 553645-75-3 (1S,3R,4R)-3-hydroxymethyl-2-azabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester 

Downstream Products

• 770737-92-3 (1S,3R,4R)-3-[(diphenylphosphanyl)-methyl]-2-azabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester 
• 553645-77-5 (1S,3R,4R)-3-benzylsulfanylmethyl-2-azabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Bicyclic O,P ligands for catalytic asymmetric 1,4-addition to α,β-unsaturated ketones

A new class of bicyclic O,P ligands has been prepared and evaluated in the 1,4-addition to α,β-unsaturated ketones. The best results with the bicyclic ligand were obtained using a lower catalyst loading than what has been reported with similar ligands whe

Synthesis and evaluation of N,S-compounds as chiral ligands for transfer hydrogenation of acetophenone

New nitrogen- and sulfur-containing compounds, bicyclic and monocyclic, were prepared and evaluated as ligands in the transfer hydrogenation of acetophenone. Utilising [Ir(COD)Cl]2 as metal precursor the best result, 80% ee, was obtained using